DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chi and Ldb2

DIOPT Version :9

Sequence 1:	NP_726403.2	Gene:	Chi / 37837	FlyBaseID:	FBgn0013764	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_034828.3	Gene:	Ldb2 / 16826	MGIID:	894670	Length:	373	Species:	Mus musculus

Alignment Length:	395	Identity:	236/395 - (59%)
Similarity:	287/395 - (72%)	Gaps:	40/395 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 PMPP--ASPFGHGGNHPMMGGPQQMERIDQGFRRHNSYFSHTEHRVFELNKRLQQRNEESDNCWW 258
            |..|  :||||     |.             :|||..|....|:|::|:|||||.|.|:|||.||
Mouse     5 PHDPFYSSPFG-----PF-------------YRRHTPYMVQPEYRIYEMNKRLQSRTEDSDNLWW 51

  Fly   259 DSFTTEFFEDDARLTILFCLEDGPKRYTIGRTLIPRFFRSIYEGGVSDLYFQLKHAKESFHNTSI 323
            |:|.||||||||.||:.|||||||||||||||||||:|.:::||||:|||:.|||:|||:||:||
Mouse    52 DAFATEFFEDDATLTLSFCLEDGPKRYTIGRTLIPRYFSTVFEGGVTDLYYILKHSKESYHNSSI 116

  Fly   324 TLDCDQCTVITQHGKPFFTKVCADARLILEFMYDDYMRIKSWHMTIKGHRELIPRSVIGTSLPPD 388
            |:|||||.::||||||.|||||.:.||||||.:||.||||:||.||:.:|||:|||::... ..|
Mouse   117 TVDCDQCAMVTQHGKPMFTKVCTEGRLILEFTFDDLMRIKTWHFTIRQYRELVPRSILAMH-AQD 180

  Fly   389 PMLLDQITKNITRAGITNSTLNYLRLCVILEPMQELMSRHKAYALSPRDCLKTTLFQKWQRMVAP 453
            |.:|||::|||||.|:||.||||||||||||||||||||||.|.|||||||||.|||||||||||
Mouse   181 PQVLDQLSKNITRMGLTNFTLNYLRLCVILEPMQELMSRHKTYNLSPRDCLKTCLFQKWQRMVAP 245

  Fly   454 PGKKDPQR-PPNKRRKRKG-----SNSGGGNNSNTPPVTNQKRSPSGPSFSLSSQ--DVMVVGEP 510
            |.  :|.| |..||||||.     |||..||.:|:  ..::|::|:. |.||::|  ||||||||
Mouse   246 PA--EPTRQPTTKRRKRKNSTSSTSNSSAGNTTNS--AGSKKKTPAA-SLSLATQVPDVMVVGEP 305

  Fly   511 TLMGGEFGEEDERLITRLENTQYDGTNAVEHDNHTGFGHADSPISGSN-PWSIDRAGAIPASPGN 574
            ||||||||:|||||||||||||||..|.:  |:...|.  :||..|:| ||: .:..|...:...
Mouse   306 TLMGGEFGDEDERLITRLENTQYDAANGM--DDEEDFN--NSPALGNNSPWN-SKPPATQETKSE 365

  Fly   575 GAAPQ 579
            .|.||
Mouse   366 NAPPQ 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chi	NP_726403.2	LIM_bind	238..440	CDD:280051	144/201 (72%)
Ldb2	NP_034828.3	LIM_bind	31..232	CDD:307769	144/201 (72%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	244..287		19/46 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..373		16/49 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836370
Domainoid	1	1.000	241	1.000	Domainoid score	I2236
eggNOG	1	0.900	-	-		E1_KOG2181
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H989
Inparanoid	1	1.050	455	1.000	Inparanoid score	I1580
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002757
OrthoInspector	1	1.000	-	-		otm44085
orthoMCL	1	0.900	-	-		OOG6_105360
Panther	1	1.100	-	-	LDO	PTHR10378
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3240
SonicParanoid	1	1.000	-	-		X1842
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.780