DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk2 and ADK1

DIOPT Version :9

Sequence 1:	NP_523836.2	Gene:	Adk2 / 37834	FlyBaseID:	FBgn0283494	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_010512.1	Gene:	ADK1 / 851812	SGDID:	S000002634	Length:	222	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	126/209 - (60%)
Similarity:	163/209 - (77%)	Gaps:	1/209 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 INAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKLGAELKKVMDAGKLVSDDLVV 83
            |..:|:||||:|||||||.|:|:|...||:||||||::|:.|::||.|.||:||.|.|||||::|
Yeast     7 IRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQGGLVSDDIMV 71

  Fly    84 DMIDSNL-DKPECKNGFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVIEFAIDDSLLVRRITGRLI 147
            :||...| :.|.|||||:|||||||:.||||||.:|.::.|.|:..||..:||.|||.|||||||
Yeast    72 NMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDELLVARITGRLI 136

  Fly   148 HQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYHKQTKPLVDYYGLRGLHFK 212
            |.|||||||:.|.|||:.|.||||||.|::||||||:||||||.|||.||:|:||:|...|:...
Yeast   137 HPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQTEPIVDFYKKTGIWAG 201

  Fly   213 VDAAKKSSDVFSTI 226
            |||::..:.|::.|
Yeast   202 VDASQPPATVWADI 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_523836.2	adk	20..233	CDD:234711	125/208 (60%)
Adk2	NP_523836.2	ADK	20..222	CDD:238713	123/202 (61%)
ADK1	NP_010512.1	adk	8..221	CDD:234711	125/208 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345523
Domainoid	1	1.000	247	1.000	Domainoid score	I353
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1227
Inparanoid	1	1.050	256	1.000	Inparanoid score	I642
Isobase	1	0.950	-	0	Normalized mean entropy	S240
OMA	1	1.010	-	-		QHG53706
OrthoFinder	1	1.000	-	-		FOG0003181
OrthoInspector	1	1.000	-	-		oto99190
orthoMCL	1	0.900	-	-		OOG6_100712
Panther	1	1.100	-	-	LDO	PTHR23359
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R630
SonicParanoid	1	1.000	-	-		X2141
TreeFam	1	0.960	-	-
	15	14.830