DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk2 and Ak9

DIOPT Version :9

Sequence 1:	NP_523836.2	Gene:	Adk2 / 37834	FlyBaseID:	FBgn0283494	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001357742.1	Gene:	Ak9 / 633979	MGIID:	2685080	Length:	1879	Species:	Mus musculus

Alignment Length:	221	Identity:	54/221 - (24%)
Similarity:	91/221 - (41%)	Gaps:	48/221 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PNAAVPVERYEPENIGINAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISS--GSKLGA 65
            |.|.:||          ..:::|||.|||.|.|..|...:.:..||.||.||..:::  .|:|..
Mouse  1374 PKATMPV----------RIMIVGPPKSGKTTVAKKLASDYGLRCLSVGDALRGMLNNHPDSELSL 1428

  Fly    66 ELKKVMDAGKLVSDDLVVDMIDSNLDKPECKN-GFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVI 129
            .|...:..||.|.|:|.:..:|.:|.:..|.. |.::||:|.|..|.:    ||:.|......:.
Mouse  1429 MLNWHLHKGKTVPDELAIQALDISLMESVCNTIGVVIDGYPVTPHQMD----LLEARSIIPMVIF 1489

  Fly   130 EFAIDDSLLVRRITGRLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYH 194
            |..:....:.:|:   |:.              ||  |:.....||    .::::.:..:...||
Mouse  1490 ELHVPSKEIFKRL---LLE--------------KK--TEQSMSYPL----HNSSQIIAYKNAKYH 1531

  Fly   195 KQTKPLVDYYG--------LRGLHFK 212
            |....:..:|.        :.|.|.|
Mouse  1532 KNINEIRQFYQKQHQNWHVIDGFHSK 1557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_523836.2	adk	20..233	CDD:234711	50/204 (25%)
Adk2	NP_523836.2	ADK	20..222	CDD:238713	50/204 (25%)
Ak9	NP_001357742.1	adk	34..286	CDD:273569
		Ribosomal_L24e_L24	<926..956	CDD:382277
		ADK	962..1177	CDD:238713
		ADK	1381..1553	CDD:238713	47/198 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900