Protein Alignment Adk2 and AK3

DIOPT Version :9

• Sequence 1: NP_523836.2
• Gene: Adk2 / 37834
• FlyBaseID: FBgn0283494
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_057366.2
• Gene: AK3 / 50808
• HGNCID: 17376
• Length: 227
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 90/225 - (40%)
• Similarity: 136/225 - (60%)
• Gaps: 15/225 - (6%)

  Fly    19 INAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKLGAELKKVMDAGKLVSDDLVV 83
            :.|:::|.|||||||.:..:...|.:.|||:||:||..:..|:::|...|..:|.|||:.||::
Human     8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVM- 71

  Fly    84 DMIDSNLDKPECKN----GFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVIEFAIDDSLLVRRITG 144
                :.|...|.||    .:||||||||:.|||.||     |...:|.||...:...::.:|:|.
Human    72 ----TRLALHELKNLTQYSWLLDGFPRTLPQAEALD-----RAYQIDTVINLNVPFEVIKQRLTA 127

  Fly   145 RLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYHKQTKPLVDYYGLRGL 209
            |.||.||||.|:.||.|||....||:||||||:|.||..|.:.|||:||..||||:::||..:|:
Human   128 RWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGV 192

  Fly   210 HFKVDAAKKSSDVFSTIDSIFQRKRPAQIQ 239
             .:..:..:::.::..:.:..|.|.|.:.|
Human   193 -LETFSGTETNKIWPYVYAFLQTKVPQRSQ 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_523836.2	adk	20..233	CDD:234711	87/216 (40%)
		ADK	20..222	CDD:238713	86/205 (42%)
AK3	NP_057366.2	ADK	12..190	CDD:395329	84/187 (45%)
		NMP. /evidence=ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|Ref.10	37..66		11/28 (39%)
		LID. /evidence=ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|Ref.10	127..164		22/36 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53706
OrthoDB	1	1.010	-	-		D1004067at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920