Protein Alignment Ak2 and AK3

DIOPT Version :10

• Sequence 1: NP_523836.2
• Gene: Ak2 / 37834
• FlyBaseID: FBgn0283494
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_057366.2
• Gene: AK3 / 50808
• HGNCID: 17376
• Length: 227
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 90/225 - (40%)
• Similarity: 136/225 - (60%)
• Gaps: 15/225 - (6%)

  Fly    19 INAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKLGAELKKVMDAGKLVSDDLVV 83
            :.|:::|.|||||||.:..:...|.:.|||:||:||..:..|:::|...|..:|.|||:.||::
Human     8 LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVM- 71

  Fly    84 DMIDSNLDKPECKN----GFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVIEFAIDDSLLVRRITG 144
                :.|...|.||    .:||||||||:.|||.||     |...:|.||...:...::.:|:|.
Human    72 ----TRLALHELKNLTQYSWLLDGFPRTLPQAEALD-----RAYQIDTVINLNVPFEVIKQRLTA 127

  Fly   145 RLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYHKQTKPLVDYYGLRGL 209
            |.||.||||.|:.||.|||....||:||||||:|.||..|.:.|||:||..||||:::||..:|:
Human   128 RWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGV 192

  Fly   210 HFKVDAAKKSSDVFSTIDSIFQRKRPAQIQ 239
             .:..:..:::.::..:.:..|.|.|.:.|
Human   193 -LETFSGTETNKIWPYVYAFLQTKVPQRSQ 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ak2	NP_523836.2	Adk	20..229	CDD:440329	86/212 (41%)
AK3	NP_057366.2	ADK	12..190	CDD:395329	84/187 (45%)
		NMP. /evidence=ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|Ref.11	37..66		11/28 (39%)
		LID. /evidence=ECO:0000255|HAMAP-Rule:MF_03169, ECO:0000269|Ref.11	127..164		22/36 (61%)