DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk2 and ak7b

DIOPT Version :9

Sequence 1:	NP_523836.2	Gene:	Adk2 / 37834	FlyBaseID:	FBgn0283494	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001103168.2	Gene:	ak7b / 504040	ZFINID:	ZDB-GENE-050309-170	Length:	699	Species:	Danio rerio

Alignment Length:	215	Identity:	53/215 - (24%)
Similarity:	84/215 - (39%)	Gaps:	44/215 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAPNAAVPVERYEPEN--IGINAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKL 63
            |..|....:|.|:...  :.|...::|||..||.|.|..:.:.:.:.|:...:.: ||.....:|
Zfish   342 MVQNIEQVIEEYKESRGLLPIRMCIVGPPAVGKSTIAEKICKHYNLHHIKLKEAI-AEALENLEL 405

  Fly    64 GAE-----------------LKKVM-DAGKLVSDDLVVDMIDSNLDKPECKN-GFLLDGFPRTVV 109
            ...                 |::.| :.|..:.|..|:.::...|....|.| ||:|||||:|..
Zfish   406 CVRTEDEENDQDDDQEFWDTLRENMNENGGRLDDQYVIRIMKDKLRTKPCMNQGFVLDGFPKTCE 470

  Fly   110 QAEKLDT-------LLDKRKTNLDAVIEFAID--DSLLVRRITGRLIHQASGRSY-HEEFAPPKK 164
            ||::|.|       |..|..|.:.....|:::  |..|..|:.........|.|| .|:|.
Zfish   471 QAKELFTGDGEPEDLESKHATKIIPEFVFSVNATDDFLKNRVLNLPETVVEGTSYMPEQFL---- 531

  Fly   165 PMTDDVTGEPLIRRSDDNAE 184
                    :.|.|..|.|.|
Zfish   532 --------QRLARFRDRNVE 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_523836.2	adk	20..233	CDD:234711	48/194 (25%)
Adk2	NP_523836.2	ADK	20..222	CDD:238713	48/194 (25%)
ak7b	NP_001103168.2	WcaG	<129..>286	CDD:223528
		NADB_Rossmann	<212..286	CDD:304358
		Adk	363..583	CDD:223637	48/194 (25%)
		ADK	363..556	CDD:238713	48/194 (25%)
		Dpy-30	656..697	CDD:253069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900