DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk2 and ak2

DIOPT Version :9

Sequence 1:	NP_523836.2	Gene:	Adk2 / 37834	FlyBaseID:	FBgn0283494	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_012812152.1	Gene:	ak2 / 448011	XenbaseID:	XB-GENE-491598	Length:	241	Species:	Xenopus tropicalis

Alignment Length:	234	Identity:	156/234 - (66%)
Similarity:	181/234 - (77%)	Gaps:	1/234 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAPNAAVPVERYEPENIGINAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKLGA 65
            |||..|.|.||..... ||.||||||||:|||||||.|.||:|||||:|||||||.::|||:||.
Frog     1 MAPREAAPAERGSVME-GIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGM 64

  Fly    66 ELKKVMDAGKLVSDDLVVDMIDSNLDKPECKNGFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVIE 130
            .||..|||||||||::||::|:.|||.|.||.|||||||||||.|||.||.||:||:..||:|||
Frog    65 RLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIE 129

  Fly   131 FAIDDSLLVRRITGRLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYHK 195
            |.:|||||||||.|||||.:|||||||||.|||:.|.||||||||:||||||...||.||||||.
Frog   130 FKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEAMKDDVTGEPLMRRSDDNETTLKSRLEAYHT 194

  Fly   196 QTKPLVDYYGLRGLHFKVDAAKKSSDVFSTIDSIFQRKR 234
            .|.|||:||...|:|..||||:....||::|.:.|.:.|
Frog   195 MTSPLVEYYQRHGIHTAVDAAQSPDVVFASILAAFSKAR 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_523836.2	adk	20..233	CDD:234711	146/212 (69%)
Adk2	NP_523836.2	ADK	20..222	CDD:238713	142/201 (71%)
ak2	XP_012812152.1	adk	19..231	CDD:234711	146/211 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	279	1.000	Domainoid score	I1670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1227
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2547
OMA	1	1.010	-	-		QHG53706
OrthoDB	1	1.010	-	-		D1004067at2759
OrthoFinder	1	1.000	-	-		FOG0003181
OrthoInspector	1	1.000	-	-		otm47829
Panther	1	1.100	-	-	LDO	PTHR23359
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R630
SonicParanoid	1	1.000	-	-		X2141
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.200