DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk2 and Ak5

DIOPT Version :9

Sequence 1:	NP_523836.2	Gene:	Adk2 / 37834	FlyBaseID:	FBgn0283494	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001102421.1	Gene:	Ak5 / 365985	RGDID:	1590818	Length:	562	Species:	Rattus norvegicus

Alignment Length:	216	Identity:	66/216 - (30%)
Similarity:	111/216 - (51%)	Gaps:	42/216 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEISSGSKLGAELKKVMDAGKLVSDDLVVDMID 87
            |:|.||||||||...|.||:...|||||::||.|::|.|:....::.:|:.|.||...:|::::.
  Rat   381 LMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLK 445

  Fly    88 ----SNLDKPECKNGFLLDGFPRTVVQAEKLDTLLDKRKTNLDAVIEFAIDDSLLVRRITGRLIH 148
                ::|...:   |||:||:||.|.|.|:....:.:.:      :...:|.|  ...:|.||:.
  Rat   446 EAMVASLGNTK---GFLIDGYPREVKQGEEFGRRIGEPQ------LVICMDCS--ADTMTNRLLQ 499

  Fly   149 QASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYHKQTKPLVDYYGLRGLHFKV 213
            ::...                       :|.:|:|:::.|||||||:.:.|::.||..:....||
  Rat   500 RSQSS-----------------------QRGEDSAKSVAKRLEAYHRASIPVIAYYETKTQLQKV 541

  Fly   214 DAAKKSSDVF----STIDSIF 230
            :|......||    :.|||:|
  Rat   542 NAEGTPDQVFLQLCTAIDSVF 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_523836.2	adk	20..233	CDD:234711	66/216 (31%)
Adk2	NP_523836.2	ADK	20..222	CDD:238713	60/202 (30%)
Ak5	NP_001102421.1	aden_kin_iso1	133..316	CDD:130427
		ADK	134..307	CDD:238713
		aden_kin_iso1	374..561	CDD:130427	64/213 (30%)
		ADK	378..550	CDD:238713	60/202 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900