DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Adk2 and F13E6.2

DIOPT Version :9

Sequence 1:	NP_523836.2	Gene:	Adk2 / 37834	FlyBaseID:	FBgn0283494	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_509786.2	Gene:	F13E6.2 / 181264	WormBaseID:	WBGene00008746	Length:	729	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	50/231 - (21%)
Similarity:	102/231 - (44%)	Gaps:	46/231 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EPENIGINA---ILLGPPGSGKGTQAPLLKEKF-CVCHLSTGDMLRAEISS--GSKLGAELKKVM 71
            ||..:..||   ::||.|||.|...:..:.:|: ....||.||:||.:|::  ..::..::.|.|
Worm   505 EPVGLPNNAPVILVLGAPGSQKNDISRRIAQKYDGFTMLSMGDILRKKINNEKNDEMWDKVSKKM 569

  Fly    72 DAGKLVSDDLVVDMIDSNLDKPECKN-GFLLDGFPRTVVQAEKLDTLLDKRKTNL----DAVIEF 131
            :.|..:...:...::...|......| |::::|:|::..|...|:..|  ::|:|    |...:|
Worm   570 NNGDPIPTKMCRTVLYEELHSRGTSNWGYVIEGYPKSPDQLVDLEHSL--QRTDLAILIDCTEQF 632

  Fly   132 AIDDSLLVRRITGRLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLEAYHKQ 196
            .::           :|::.:..:                      :||||:::|::.|:|.:.|.
Worm   633 CLE-----------VINKRNREN----------------------KRSDDDSDAVRSRMEYFKKN 664

  Fly   197 TKPLVDYYGLRGLHFKVDAAKKSSDVFSTIDSIFQR 232
            |.|::.....:|....||.......||..:..:..|
Worm   665 TLPMLKTLDDKGKLRVVDGDADPDTVFKEVVQVIDR 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_523836.2	adk	20..233	CDD:234711	48/224 (21%)
Adk2	NP_523836.2	ADK	20..222	CDD:238713	45/212 (21%)
F13E6.2	NP_509786.2	aden_kin_iso1	168..355	CDD:130427
		ADK	171..337	CDD:238713
		aden_kin_iso1	514..699	CDD:130427	45/219 (21%)
		ADK	515..690	CDD:238713	43/209 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900