DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk2 and ak5

DIOPT Version :9

Sequence 1:	NP_523836.2	Gene:	Adk2 / 37834	FlyBaseID:	FBgn0283494	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001093554.1	Gene:	ak5 / 100003595	ZFINID:	ZDB-GENE-030131-8256	Length:	563	Species:	Danio rerio

Alignment Length:	244	Identity:	65/244 - (26%)
Similarity:	113/244 - (46%)	Gaps:	53/244 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VERYE--------PENIGINAILLGPPGSGKGTQAPLLKEKFCVCHLSTGDMLRAEI---SSGSK 62
            :|.||        |:.|    :::|.||||||||...:.|::...::|.|::||.::   ::.::
Zfish   119 IEEYEVFDPSRPRPKVI----LIIGGPGSGKGTQCLKIAERYGFEYVSVGELLRKKMIHNATSNR 179

  Fly    63 LGAELKKVMDAGKLVSDDLVVDMIDSNLDK-PECKNGFLLDGFPRTVVQAEKLDTLLDKRKTNLD 126
            ..:.:.:::..|:|...:..:..|...:.| ||. :|.::|||||.|.||...:   |:..|. |
Zfish   180 KWSLIARIITNGELAPQETTITEIKQKIMKIPEA-SGIVIDGFPRDVGQALSFE---DQVCTP-D 239

  Fly   127 AVIEFAIDDSLLVRRITGRLIHQASGRSYHEEFAPPKKPMTDDVTGEPLIRRSDDNAEALKKRLE 191
            .|:..|..:..|..|:..|...|.                           |.|||.:|:.:||.
Zfish   240 LVVFLACSNQRLKERLEKRAEQQG---------------------------RPDDNPKAIDRRLT 277

  Fly   192 AYHKQTKPLVDYYGLRGLHFKVDAAKKSSDVF----STIDS-IFQRKRP 235
            .:.:...|||.|:..:||...:||.:...:||    .|:|: :|..|.|
Zfish   278 NFKQNAIPLVKYFQEKGLIVTLDADRDEEEVFYDISMTVDNKLFPTKEP 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk2	NP_523836.2	adk	20..233	CDD:234711	58/221 (26%)
Adk2	NP_523836.2	ADK	20..222	CDD:238713	53/205 (26%)
ak5	NP_001093554.1	aden_kin_iso1	133..317	CDD:130427	57/219 (26%)
		ADK	134..308	CDD:238713	54/209 (26%)
		aden_kin_iso1	375..562	CDD:130427
		ADK	379..552	CDD:238713
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900