Protein Alignment Xxylt and GLT8D2

DIOPT Version :10

• Sequence 1: NP_611871.2
• Gene: Xxylt / 37833
• FlyBaseID: FBgn0034959
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_001371641.1
• Gene: GLT8D2 / 83468
• HGNCID: 24890
• Length: 354
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 85/421 - (20%)
• Similarity: 136/421 - (32%)
• Gaps: 132/421 - (31%)

  Fly    60 LLRCRWQKKLVLLLIFICVCVLIVFANTHLLVRGNILSAFLSSRLNKHSHAEKQEA--RYPDIPA 122
            |||...|..|.||::.:||   |::...|   :|.:               .|.:|  .:||..:
Human     3 LLRKINQVLLFLLIVTLCV---ILYKKVH---KGTV---------------PKNDAVFMFPDDES 46

  Fly   123 TTP-----SVPPV-------LRPTHYLLN--YSSTQLELSSHLNGLSSDYNIFVIYTREN--YHL 171
            .||     .:|.|       :..|...:|  ||:|...:..::.||.:.......:...:  ..:
Human    47 ETPEELEEEIPVVICAAAGRMGATMAAINSIYSNTDANILFYVVGLRNTLTRIRKWIEHSKLREI 111

  Fly   172 NLKFDLFAHSLLKHTSAQLHLHVITDSESQPSVLEILQRQIRRF--------RRTVIYTIYDVKV 228
            |.|...|...:||..        |....|:|.:|:.|  ...||        ...|||...|| :
Human   112 NFKIVEFNPMVLKGK--------IRPDSSRPELLQPL--NFVRFYLPLLIHQHEKVIYLDDDV-I 165

  Fly   229 CSSIIQDIAAKLSPYFSSTPNSYYSDSLFFLSLGLHRIADRSLNRAILLDCDIVFRSDVRLLF-- 291
            ....||::       :.:|           |:|| |..|...       |||:....|:..|.
Human   166 VQGDIQEL-------YDTT-----------LALG-HAAAFSD-------DCDLPSAQDINRLVGL 204

  Fly   292 -NEFDNFLPHQLYGLAPELTPVYRHILYRYRVRYPKTSFGNPYYPINNEGGNQHSRVHHGYPGLN 355
             |.:..:|.             ||....:.....|.|...||...:.|....:|.|:
Human   205 QNTYMGYLD-------------YRKKAIKDLGISPSTCSFNPGVIVANMTEWKHQRI-------- 248

  Fly   356 SGVVLLLLNRIRNSKSYLEKLTHSEVHTLVAKYSFKGHLGDQDFFTLLGYEYPNLIYRLDCIWNR 420
                          ...|||.....|...:...|..|.:.......:...:|..    ::.:|:.
Human   249 --------------TKQLEKWMQKNVEENLYSSSLGGGVATSPMLIVFHGKYST----INPLWHI 295

  Fly   421 QLCTWWKDHGYSQIFDAYFRCEGNIKMYHGN 451
            :...|..|..||:    :|..|.  |:.|.|
Human   296 RHLGWNPDARYSE----HFLQEA--KLLHWN 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xxylt	NP_611871.2	Glyco_tranf_GTA_type	172..>422	CDD:472172	49/260 (19%)
GLT8D2	NP_001371641.1	Glyco_tranf_GTA_type	56..341	CDD:472172	67/347 (19%)