DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Xxylt and Large2

DIOPT Version :9

Sequence 1:	NP_611871.2	Gene:	Xxylt / 37833	FlyBaseID:	FBgn0034959	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	XP_006234624.1	Gene:	Large2 / 311202	RGDID:	735214	Length:	715	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	94/333 - (28%)
Similarity:	142/333 - (42%)	Gaps:	91/333 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 NYSSTQLEL-------SSHLNGLSSDYNIFVIYTRENYHLNLKFDLFAHSLLKHTSAQLHLHVIT 196
            |.|::.|:|       ..|:..:.:.||    .:||...|       ..|:|.:....||||:||
  Rat    75 NRSTSSLQLLLPPKCEMLHVAIVCAGYN----SSREIITL-------MKSVLFYRKNPLHLHLIT 128

  Fly   197 DSESQPSVLEILQRQIRRFRR----TVIYTIYDVKVCSSIIQDIAAKLSPYFSSTPNSYYSDSLF 257
            |:.:: ::||.|      ||.    .|:.:.||           |.:|.|..|..||.:||....
  Rat   129 DAVAR-NILETL------FRTWMVPAVVVSFYD-----------AEELKPLVSWIPNKHYSGLYG 175

  Fly   258 FLSLGLHRIADRSLNRAILLDCDIVFRSDVRLLFNEFDNFLPHQLYGLAPELTPVYRHILYRYRV 322
            .:.|.|..:...||.|.|:||.|:.|.||:..|:..|.:|...|:.||....:..|
  Rat   176 LMKLVLPSVLPLSLARVIVLDTDVTFSSDIMELWALFGHFSDKQVVGLVENQSDWY--------- 231

  Fly   323 RYPKTSFGNPYYPINNEGGNQHSRVHHGYP----GLNSGVVLLLLNRIRN-SKSYLEKLT-HSEV 381
                  .||.:            :.|..:|    |.|:||:||.|:|::. ....:.||| ..|:
  Rat   232 ------LGNLW------------KNHRPWPALGRGFNTGVILLWLDRLQQIGWEQMWKLTAKREL 278

  Fly   382 HTLVAKYSFKGHLGDQDFFTLLGYEYPNLIYRLDCIWNRQLCTWWKDHGYSQIFDAYFRC---EG 443
            .||.|.     .|.|||.|..:..|:|.|::.|.|:||.||    .||..::      ||   ..
  Rat   279 LTLTAT-----SLADQDIFNAVIKEHPELVHPLPCVWNVQL----SDHTLAE------RCYLEAA 328

  Fly   444 NIKMYHGN 451
            ::|:.|.|
  Rat   329 DLKVIHWN 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xxylt	NP_611871.2	Glyco_tranf_GTA_type	172..>422	CDD:299700	75/259 (29%)
Large2	XP_006234624.1	GT8_LARGE_C	92..371	CDD:133053	90/316 (28%)
		RfaJ	93..>340	CDD:224359	90/315 (29%)
		Glyco_transf_49	426..660	CDD:290607
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I8078
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810