DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Xxylt and Large2

DIOPT Version :9

Sequence 1:	NP_611871.2	Gene:	Xxylt / 37833	FlyBaseID:	FBgn0034959	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	XP_006499317.1	Gene:	Large2 / 228366	MGIID:	2443769	Length:	715	Species:	Mus musculus

Alignment Length:	410	Identity:	107/410 - (26%)
Similarity:	166/410 - (40%)	Gaps:	114/410 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 VLLLIFICVCVLIVFANT-------------HLLVRGNILSAFLSSRLNKHSHAEKQEARYPDIP 121
            ||||:.:.|....:|...             .|..|..:.....|..|...:..::...|..::.
Mouse    14 VLLLLLLLVVGFFLFGRDPDCKRRSWAGEEGTLCDRCLLTPRVFSDGLGTTATLDEDPYRSRNLS 78

  Fly   122 ATTPS--VPPVLRPTHYLLNYSSTQLELSSHLNGLSSDYNIFVIYTRENYHLNLKFDLFAHSLLK 184
            |::|.  :||.....|..:               :.:.||    .:||...|       ..|||.
Mouse    79 ASSPQLLLPPKCEMLHVAI---------------VCAGYN----SSREIITL-------TKSLLF 117

  Fly   185 HTSAQLHLHVITDSESQPSVLEILQRQIRRFRR----TVIYTIYDVKVCSSIIQDIAAKLSPYFS 245
            :....||||:|||:.:: ::||.|      ||.    .|:.:.||           |.:|.|..|
Mouse   118 YRKNPLHLHLITDAVAR-NILETL------FRTWMVPAVVVSFYD-----------AEELKPLVS 164

  Fly   246 STPNSYYSDSLFFLSLGLHRIADRSLNRAILLDCDIVFRSDVRLLFNEFDNFLPHQLYGLAPELT 310
            ..||.:||.....:.|.|..|...||.|.|:||.|:.|.||:..|:..||:|...|:.||....:
Mouse   165 WIPNKHYSGLYGLMKLVLPSILPPSLARVIVLDTDVTFSSDIVELWALFDHFSDKQVVGLVENQS 229

  Fly   311 PVYRHILYRYRVRYPKTSFGNPYYPINNEGGNQHSRVHHGYP----GLNSGVVLLLLNRIRNSK- 370
            ..|               .||.:            :.|..:|    |.|:||:||.|:|::.:.
Mouse   230 DWY---------------LGNLW------------KNHRPWPALGRGFNTGVILLWLDRLQQTGW 267

  Fly   371 SYLEKLT-HSEVHTLVAKYSFKGHLGDQDFFTLLGYEYPNLIYRLDCIWNRQLCTWWKDHGYSQI 434
            ..:.|:| ..|:.||:|.     .|.|||.|..:..|:|:|::.|.|:||.||    .||..::
Mouse   268 EQMWKVTAKRELLTLMAT-----SLADQDIFNAVIKEHPHLVHPLPCVWNVQL----SDHTRAE- 322

  Fly   435 FDAYFRC---EGNIKMYHGN 451
                 ||   ..::|:.|.|
Mouse   323 -----RCYLEAADLKVIHWN 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xxylt	NP_611871.2	Glyco_tranf_GTA_type	172..>422	CDD:299700	77/259 (30%)
Large2	XP_006499317.1	GT8_LARGE_C	93..372	CDD:133053	92/331 (28%)
Large2	XP_006499317.1	Glyco_transf_49	427..660	CDD:372794
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3765
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810