DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Xxylt and large1

DIOPT Version :9

Sequence 1:	NP_611871.2	Gene:	Xxylt / 37833	FlyBaseID:	FBgn0034959	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	XP_031754415.1	Gene:	large1 / 100498555	XenbaseID:	XB-GENE-6250446	Length:	754	Species:	Xenopus tropicalis

Alignment Length:	439	Identity:	99/439 - (22%)
Similarity:	164/439 - (37%)	Gaps:	113/439 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 CRWQKKLVL--LLIFICVCVLIVFANTHLLVRGNILSAFLSSRLNKHSHAEKQEARYPDIPATTP 125
            ||.::|.:|  |.:.....:..::..|.....|..:|.   |.|:...|:.:..|     |:...
Frog     5 CRGRRKFLLASLTLLFVPAITWIYLFTGNFDNGKTVSL---SPLDAQPHSPRYLA-----PSQRE 61

  Fly   126 SVPPVLRPTHYLLNYSSTQLELS-----SHLNG-LSSDYN------------------------- 159
            |:...:|...........||.|:     ||.:| .|..|:
Frog    62 SLEVRVREVEEENRLLRKQLSLAQGRGPSHRHGNRSKTYSMEEGTGDSESLRAGIVAGNSSECGQ 126

  Fly   160 ---------IFVIYTRENYHLNLKFDLFAHSLLKHTSAQLHLHVITDSESQPSVLEILQRQIRRF 215
                     |.|......|:.:........|:|.|....||.|:|.|:                .
Frog   127 LPAVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADT----------------I 175

  Fly   216 RRTVIYTIYDVKVCSSIIQDI--AAKLSPYFSSTPNSYYSDSLFFLSLGLHRIADRSLNRAILLD 278
            .:.::.|::...:..::..|.  |.:|....|..||.:||.....:.|.|.:....||.|.|:||
Frog   176 AKQILATLFQTWMVPAVRVDFYDADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPASLERVIVLD 240

  Fly   279 CDIVFRSDVRLLFNEFDNFLPHQLYGLAPELTPVYRHILYRYRVRYPKTSFGNPYYPINNEGGNQ 343
            .||.|.:|:..|:..|..|...|:.||....:..|               .||.:
Frog   241 TDITFATDIAELWAVFHKFKGQQVLGLVENQSDWY---------------LGNLW---------- 280

  Fly   344 HSRVHHGYP----GLNSGVVLLLLNRIRNSK-SYLEKLT-HSEVHTLVAKYSFKGHLGDQDFFTL 402
              :.|..:|    |.|:||:||||:::|..| ..:.:|| ..|:.::::.     .|.|||.|..
Frog   281 --KNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMSMLST-----SLADQDIFNA 338

  Fly   403 LGYEYPNLIYRLDCIWNRQLCTWWKDHGYSQIFDAYFRCEGNIKMYHGN 451
            :..:.|.|:::|.|.||.||    .||..|   :..:|...::|:.|.|
Frog   339 VIKQNPFLVHQLPCFWNVQL----SDHTRS---EQCYRDVSDLKVIHWN 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xxylt	NP_611871.2	Glyco_tranf_GTA_type	172..>422	CDD:299700	64/257 (25%)
large1	XP_031754415.1	GT8_LARGE_C	136..415	CDD:133053	76/300 (25%)
large1	XP_031754415.1	Glyco_transf_49	471..740	CDD:404735
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8825
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000