DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Xxylt and large2

DIOPT Version :9

Sequence 1:	NP_611871.2	Gene:	Xxylt / 37833	FlyBaseID:	FBgn0034959	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001096468.1	Gene:	large2 / 100125087	XenbaseID:	XB-GENE-5871953	Length:	723	Species:	Xenopus tropicalis

Alignment Length:	444	Identity:	106/444 - (23%)
Similarity:	161/444 - (36%)	Gaps:	148/444 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 LRCRWQKKLVLLLIFICVCVLIVFANTHLLVRGNILSAFLSSRLNKHSHAEKQEARYPDIPATTP 125
            |.||.:.|      |:.:.:|::.|.|.|         :||          ..|..|      .|
Frog     3 LSCRSKAK------FLALALLLLSAATWL---------YLS----------VGETEY------GP 36

  Fly   126 SVPPVLRPTHYLLNYSSTQLELSSHLN-------------------------GLSSDYNIFVIYT 165
            |:.||  ..|:... .|.||||.|.|.                         |...|.:...
Frog    37 SLGPV--APHFSAT-PSLQLELESRLRVAEEENRRLRQQLGEMRNEEQSTGVGTEGDNSSHC--- 95

  Fly   166 RENYHLNLKFDL------------------FAHSLLKHTSAQLHLHVITDSESQPSVLEILQRQI 212
             |:..|..|.:|                  ...|:|.|....||||:|||:.:    |.:|....
Frog    96 -EHRSLTEKCELIHVAIVCAGHNSSRDVVTLVKSILFHRRNPLHLHLITDAVA----LRVLGNLF 155

  Fly   213 RRFR-RTVIYTIYDVKVCSSIIQDIAAKLSPYFSSTPNSYYSDSLFFLSLGLHRIADRSLNRAIL 276
            :.:. .::..:.|:           |::|.|..:..||.:||.....|.|.|.:.....|::.|:
Frog   156 KTWMVPSLQISFYN-----------ASELKPDVAWIPNKHYSGIYGLLKLTLTKALPSDLSKVIV 209

  Fly   277 LDCDIVFRSDVRLLFNEFDNFLPHQLYGLAPELTPVYRHILYRYRVRYPKTSFGNPYYPINNEGG 341
            ||.||.|.:|:..|:..|..|...|:.||....:..|...|::....:|  :.|.
Frog   210 LDTDITFATDIAELWAIFKKFTGEQVLGLVENQSDWYLGNLWKNHKPWP--ALGR---------- 262

  Fly   342 NQHSRVHHGYPGLNSGVVLLLLNRIRNSKSYLEKLTHSEVHTLVAKYSFKG----HLGDQDFFTL 402
                       |.|:||:||||:::|       .:...|:..|.|:.....    .|.|||.|..
Frog   263 -----------GFNTGVILLLLDKLR-------LIGWEEMWRLTAERELMNMLSTSLADQDIFNA 309

  Fly   403 LGYEYPNLIYRLDCIWNRQLCTWWKDHG-----YSQIFDAYFRCEGNIKMYHGN 451
            :....|.|:|:|.|.||.||    .||.     ||::.|        :|:.|.|
Frog   310 VIKSSPTLVYQLPCYWNVQL----SDHTRSEQCYSELAD--------LKVIHWN 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xxylt	NP_611871.2	Glyco_tranf_GTA_type	172..>422	CDD:299700	67/272 (25%)
large2	NP_001096468.1	GT8_LARGE_C	107..386	CDD:133053	75/302 (25%)
large2	NP_001096468.1	Glyco_transf_49	440..709	CDD:290607
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8825
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000