DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3907 and Efcab14

DIOPT Version :9

Sequence 1:	NP_611870.3	Gene:	CG3907 / 37832	FlyBaseID:	FBgn0034958	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	XP_038965520.1	Gene:	Efcab14 / 298425	RGDID:	1310351	Length:	523	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	100/434 - (23%)
Similarity:	166/434 - (38%)	Gaps:	117/434 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 MKKRRELDALI----------ASQSSSGKRANRRVPGGTNSQDKLLSVSTDDPEDYAWTNVAGSR 71
            ||||:||:|||          ..|.||..|..|..|..::      |.|:.:.|::   ...|:|
  Rat     1 MKKRKELNALIGLAGDSRRKKTKQGSSSHRLLRTEPPDSD------SASSSEEEEF---GAIGNR 56

  Fly    72 RSHRKIAYFR---MCGPL-LFGIMGILIVGI--LYWLYFDLRQQLTDYRQKIEEVSAMSKNFPDT 130
            ....|..|.|   :|.|| .|.|:...:|..  |.|:...|::.|...::|..   .|..|...:
  Rat    57 SRFVKGDYVRCCKICYPLCAFVILAACVVACVGLVWMQMALKEDLDVLKEKFR---TMESNQKSS 118

  Fly   131 LQRWHETSSYLLKNQ-------------TAVISEINDLQKSMESLRNNFSNLEAAVAAQRN---- 178
            .|...:.:..||..:             :.|.:.|.::.|.:..|.:..::|:|.|.:..:
  Rat   119 FQEIPKLNEELLSKEKQLEKIESGELGLSRVWTNITEMNKQISLLSSAVNHLKANVKSAADLLSL 183

  Fly   179 ----HGKDEKLVADFGAKIEAVATDIEAIKEHYNKYTEVQKTLQAETEALKLNLSQLPTIQANAL 239
                .|. :|.||..|..:.:|:..:|||          |||:......|:|....:.|..:|.:
  Rat   184 PSTVEGL-QKSVASIGNTLNSVSLAVEAI----------QKTVDEHKATLELLQGSVETNGSNQI 237

  Fly   240 ------PANLSDDIAALNKTTFNSFK----LLANDLKNVNNTLSQTTKILSEEISLHKTKIDDLL 294
                  |:.|.      |:|...|.|    .|.|.|:.||:|:          :...:.....|.
  Rat   238 MPSPPPPSELD------NRTHSESAKQDILYLHNSLEEVNSTV----------VGYQRQNDLKLK 286

  Fly   295 DRSENITSHVATISNSWPEYKQKVTSFDESLERIEKEITLANNKNNMLAASVDQLKNFCIQSMGN 359
            ..||       |:||           ..:.|:.||.::        :..:..:|..|.....|||
  Rat   287 GMSE-------TLSN-----------LTQRLDLIESDV--------VALSKAEQRTNVSSSMMGN 325

  Fly   360 IKAPSSEDGSVVPKPEAIAVKQEVIKPSANATVK---LQESLKL 400
            ..|....:.|:..:.:  |||.:.||...|:..:   |:|.|:|
  Rat   326 RAASLKRESSMTNRTD--AVKAQSIKKEDNSNSQVSGLREKLQL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3907	NP_611870.3	LXG	147..351	CDD:282581	45/221 (20%)
Efcab14	XP_038965520.1	Smc	<97..>344	CDD:224117	60/304 (20%)
Efcab14	XP_038965520.1	EFh	427..478	CDD:415501
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870