Protein Alignment Rsph4a and Rsph4a

DIOPT Version :10

• Sequence 1: NP_611869.1
• Gene: Rsph4a / 37831
• FlyBaseID: FBgn0034957
• Length: 708
• Species: Drosophila melanogaster
• Sequence 2: NP_001156429.1
• Gene: Rsph4a / 212892
• MGIID: 3027894
• Length: 716
• Species: Mus musculus
• Alignment Length: 765
• Identity: 232/765 - (30%)
• Similarity: 341/765 - (44%)
• Gaps: 199/765 - (26%)

  Fly    15 SSSHFAPP---------------PVCAPRRKKPEKPAAEEASP-------------ECSNVTSSS 51
            |||...||               ||.|...:|.....|:..:|             ..|:.||.:
Mouse    80 SSSPPPPPLQFHSTPLNTETTQDPVAASPTEKTANGIADTGTPYSDPWESSSAAKQSTSHYTSHA 144

  Fly    52 SSSTTTISIGAFDSQCNLHNA-RN----------------------PEAPNIG----------YE 83
            ..||...|.......|.|.:| ||                      |:.|.:|          ..
Mouse   145 EESTFPQSQTPQPDLCGLRDASRNKSKHKGLRFDLLQEEGSDSNCDPDQPEVGASEAAQSMLEVA 209

  Fly    84 LNVAKSILQKYSTLSGDNLFDHLSDIIKRVIDERPPNVIDFFEEFSRNVREQKFHLP-------- 140
            :..||:.|...|:.||.||:||||.::.:::||||.:.:|..|..|::|:...|:..
Mouse   210 IQNAKAYLLSTSSKSGLNLYDHLSKVLTKILDERPADAVDIIENISQDVKMAHFNKKLDTLHNEY 274

  Fly   141 ERFPPSGVFDEVRSFRVAKKILQSMKLPYVVEGEDLMGEDLSVEDLRTNEDMRIVIDDSMRYFVT 205
            |..|             |.:|.::.|..: ::|. |.|.|..:|:......:..|::.:
Mouse   275 EMLP-------------AYEIAETQKALF-LQGH-LEGADSELEEEMAESSLPNVMESA------ 318

  Fly   206 FNERVQQLQFYWTQCGFSISNDDIFQLASAMNRL-QTHPSIMQCRFWGCINGLKASYYIVEASLT 269
                     :|:.|.|..:..|:.:::..|:.:| .||| |.:|||||.|.||:.:|.:.|....
Mouse   319 ---------YYFEQAGVGLGTDETYRVFLALKQLTDTHP-IQRCRFWGKILGLEMNYIVAEVEFR 373

  Fly   270 REEIASRLVMMEEEMRQKQIPFPMRKDREDKPPPAHIGPELTPGIYGWEEFPPEELEKMKPKAAP 334
            ..|       .|||:.::.|    .::|::....|           |.||  .|||.|...||..
Mouse   374 DGE-------DEEEVEEEGI----AEERDNGGSEA-----------GEEE--EEELPKSLYKAPQ 414

  Fly   335 VPLVEEMELYDIPPEFIGKGCNRYSYFVVNSLFDDWIELPIVTPRQIVVSRQIKKFLTGDLEADV 399
            |          ||.|....|.|:|.|||.|.....|:.||.|||.|||.:|:||||.||.|:|.|
Mouse   415 V----------IPKEESRTGANKYVYFVCNVPGRPWVRLPSVTPAQIVTARKIKKFFTGRLDAAV 469

  Fly   400 ISYPCFPGKEKHYLRTLIGRITAGTYIAPVGYYRRMTKKEQRMFDGEEEEEGEEEEEEEEEEEFN 464
            ||||.|||.|.:|||..|.||:|||:::|:|:|:         |.   ||||||||.|...:.:.
Mouse   470 ISYPPFPGNESNYLRAQIARISAGTHVSPLGFYQ---------FG---EEEGEEEEVEGGRDSYE 522

  Fly   465 EGEE-EQIEDNDVMLLKNEKYEAEPLGSLATPVAWVHVRSNILNQQGRVVWYDEEKARKEREKAL 528
            |..: |.|:..|::         |.|.:      |||....|| .|||..|::
Mouse   523 ENPDFEGIQVIDLV---------ESLSN------WVHHVQYIL-PQGRCNWFN------------ 559

  Fly   529 ALYLKMQMLGEMEEEVEEEEDEEEGEEEGEEEGMIEGFNQPELGPSILSSCANDMNPEVPVSWLA 593
                      .::::.:|||:|||.||:|||...||    .|:||.:|:..:.|:..:...||..
Mouse   560 ----------PIQKDEDEEEEEEEDEEKGEEPDYIE----QEVGPPLLTPISEDLGIQNIPSWTT 610

  Fly   594 RMTSKYTNQKERMLVMQSNVWPGAYTFIFEKTCESIYLGWGHKYYARNIPFKHLPMVQEEFPHNP 658
            :::|....| ..:.|::||:|||||.|...|..|:.|:||||||...|......|.|.:|:|..|
Mouse   611 QLSSNLIPQ-YAIAVLRSNLWPGAYAFSNGKKFENFYIGWGHKYCVENYTPPSPPPVYQEYPSGP 674

  Fly   659 EDFVEANDPTVEEEEAYKAWLLRKQQKAEYVAEDIEDYDDDEFADQYDDD 708
            | ..|.|||:||||:|::       ...|.||...|:.:..|..|:.|:|
Mouse   675 E-ITEMNDPSVEEEQAFR-------MTQEPVALSTEENEGTEDEDEDDED 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rsph4a	NP_611869.1	Radial_spoke	87..637	CDD:461405	181/559 (32%)
Rsph4a	NP_001156429.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..167		31/147 (21%)
		Radial_spoke	213..653	CDD:461405	138/441 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	374..413		11/38 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	564..586		8/21 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	668..716		20/47 (43%)