Protein Alignment CG3860 and HES1

DIOPT Version :10

• Sequence 1: NP_001286802.1
• Gene: CG3860 / 37825
• FlyBaseID: FBgn0034951
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_014880.3
• Gene: HES1 / 854412
• SGDID: S000005763
• Length: 434
• Species: Saccharomyces cerevisiae
• Alignment Length: 472
• Identity: 101/472 - (21%)
• Similarity: 154/472 - (32%)
• Gaps: 165/472 - (34%)

  Fly    26 SIWAILKNCIGK---DLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPA--------- 78
            |.|......|..   |||.::.|..:..|.|    |.|:.:|        ..||||
Yeast     8 SSWTSFLKSISSFNGDLSSLSAPPFILSPTS----LTEFSQY--------WAEHPALFLEPSLID 60

  Fly    79 -------------------DRMKYVAAFAVSALASNW----ERLG---KPFNPLLGETY------ 111
                               .:|..|..:.:|.|.|.:    |.:|   ||.||.|||.:
Yeast    61 GENYKDHCPFDPNVESKEVAQMLAVVRWFISTLRSQYCSRSESMGSEKKPLNPFLGEVFVGKWKN 125

  Fly   112 --ELQKGDYRIVCEQVSHHPPVSAFHA--ESKDFKFHGTISPKIKFWGK-SVEVNPKGTVTVEFP 171
              ..:.|:..::.||||||||::||..  |..|....|....|..|... ::.|.|.|.|.::..
Yeast   126 DEHPEFGETVLLSEQVSHHPPMTAFSIFNEKNDVSVQGYNQIKTGFTKTLTLTVKPYGHVILKIK 190

  Fly   172 KWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAG--SGAKNLHRVEGF- 233
              :|:|..|.....:..|:|...::|..|:..|.: :.|.:..:.|...|  :|.||..:...:
Yeast   191 --DETYLITTPPLHIEGILVASPFVELGGRSFIQS-SNGMLCVIEFSGRGYFTGKKNSFKARIYR 252

  Fly   234 ---VKDASETNLYFLYGKWTEFIKCCSAESYV--QFLKQGTRKNDDYDGSPNGTPKKMFSKLNSF 293
               .....|..||.:.|:|:........:|.|  ||          ||.|...|...:..
Yeast   253 SPQEHSHKENALYLISGQWSGVSTIIKKDSQVSHQF----------YDSSETPTEHLLVK----- 302

  Fly   294 KLNSFRSLSIQDVSSDSYPPMEQEGDIPKSDSAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFAL 358
                               |:|::..:            :|...|.
Yeast   303 -------------------PIEEQHPL------------ESRRAWK------------------- 317

  Fly   359 QLNAMDSNMKPPLTLCPTDSRLRPDILH-LEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWS 422
                                    |:.. :.:||:....|.|..||.|||..|:|.: ....:|.
Yeast   318 ------------------------DVAEAIRQGNISMIKKTKEELENKQRALREQER-VKGVEWQ 357

  Fly   423 PRWFKYA--TNPHTKID 437
            .||||..  .|.:|..|
Yeast   358 RRWFKQVDYMNENTSND 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3860	NP_001286802.1	Oxysterol_BP	26..450	CDD:460126	101/472 (21%)
HES1	NP_014880.3	Oxysterol_BP	12..365	CDD:460126	96/457 (21%)