DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3860 and ORP1D

DIOPT Version :9

Sequence 1:	NP_001286802.1	Gene:	CG3860 / 37825	FlyBaseID:	FBgn0034951	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001184980.1	Gene:	ORP1D / 837875	AraportID:	AT1G13170	Length:	837	Species:	Arabidopsis thaliana

Alignment Length:	481	Identity:	159/481 - (33%)
Similarity:	216/481 - (44%)	Gaps:	115/481 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQ--- 73
            |..||......|.|.:|:|:|..||||||.:.:||..|||||.||:..|.:||:.|:..|.:
plant   419 RDNLPEPKEKEKPVGLWSIIKENIGKDLSGVCLPVYFNEPLSSLQKCFEDLEYSYLIDRALEWGK 483

  Fly    74 ---------------------QEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGD 117
                                 |.:...|:..:||||||..||...|..||||||||||||   .|
plant   484 QVRSFSLFLILVRYRKEWFILQGNELMRILNIAAFAVSGYASTEGRQCKPFNPLLGETYE---AD 545

  Fly   118 Y-----RIVCEQVSHHPPVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESY 177
            |     |...|:|||||.:.|.|.|.:.:.|.|..:.|.||||:|::::|.|.:|::|.. .|.|
plant   546 YPDKGLRFFSEKVSHHPMIVACHCEGQGWNFWGDSNIKGKFWGRSIQLDPVGVLTLKFDD-GEIY 609

  Fly   178 SWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKD-ASETN 241
            .|:.|...::|||:|:|:.:.||.|.|.. .:.:...|.||......:|..:|.|||:| .:...
plant   610 QWSKVTTSIYNIILGKLYCDHYGTMRIKG-GSNYSCRLKFKEQSVIDRNPRQVHGFVQDNRTGEK 673

  Fly   242 LYFLYGKWTEFIKCCSAESYVQFLKQGTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDV 306
            :..|.|||.|      |..||.             |.|...||
plant   674 VAILIGKWDE------AMYYVL-------------GDPTTKPK---------------------- 697

  Fly   307 SSDSYPPMEQEGDIPKSDSAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPL 371
               .|.||                 .::..||.....|:...  |..:.||:.||.:...|...|
plant   698 ---GYDPM-----------------TEAVLLWERDKSPTKTR--YNLSPFAISLNEITPGMIDKL 740

  Fly   372 TLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTRK-QRKSTNSDDWSPRWFKYATNPHTK 435
            .  |||||||||..|||.|..:.|:.||.|||:.||..|: |.|.     |.||||:     ..:
plant   741 P--PTDSRLRPDQRHLENGEYESANAEKLRLEQLQRQARRLQEKG-----WKPRWFE-----KDE 793

  Fly   436 IDDWLYSGGYWD----RKYDNTDTIF 457
            ..::.|.||||:    :.:|....||
plant   794 EGNYRYLGGYWEAREKKDWDRITDIF 819

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3860	NP_001286802.1	Oxysterol_BP	26..441	CDD:279564	146/445 (33%)
ORP1D	NP_001184980.1	PH-like	95..234	CDD:302622
		PH	97..225	CDD:278594
		Oxysterol_BP	434..794	CDD:279564	146/439 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	260	1.000	Domainoid score	I482
eggNOG	1	0.900	-	-		E1_KOG1737
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D863978at2759
OrthoFinder	1	1.000	-	-		FOG0000898
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820