DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3860 and ORP1C

DIOPT Version :9

Sequence 1:	NP_001286802.1	Gene:	CG3860 / 37825	FlyBaseID:	FBgn0034951	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001319881.1	Gene:	ORP1C / 826368	AraportID:	AT4G08180	Length:	814	Species:	Arabidopsis thaliana

Alignment Length:	457	Identity:	153/457 - (33%)
Similarity:	220/457 - (48%)	Gaps:	85/457 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DYAEHVERTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLT 69
            :|.....|..||..:...|.||:|:::|:.|||||:|:.:||..|||||.||:..|.:||:.||.
plant   416 NYPRVKRRKNLPDPVEKEKSVSLWSMIKDNIGKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLLD 480

  Fly    70 EA---AQQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGDY-----RIVCEQVS 126
            .|   .::.:...|:..|||||||..||...|:.||||||||||||   .||     |...|:||
plant   481 RAFEYGKRGNSLMRILNVAAFAVSGYASTEGRICKPFNPLLGETYE---ADYPDKGLRFFSEKVS 542

  Fly   127 HHPPVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIV 191
            |||.|.|.|.:...:||.|..:.:.||||:|::::|.|.:|::|.. .|...|:.|...::|:|:
plant   543 HHPMVVACHCDGTGWKFWGDSNLRSKFWGRSIQLDPVGVLTLQFDD-GEILQWSKVTTSIYNLIL 606

  Fly   192 GRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYFLYGKWTEFIKCC 256
            |:|:.:.||.|.|...|. :...|.||......:|.|:|.|.|::.|...:..::|||.|
plant   607 GKLYCDHYGTMRIEGSAE-YSCKLKFKEQSIIDRNPHQVHGIVQNKSGKTVATMFGKWDE----- 665

  Fly   257 SAESYVQFLKQGTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDVSSDSYPPMEQEGDIP 321
                                                         ||..|:.|.
plant   666 ---------------------------------------------SIHFVTGDC----------- 674

  Fly   322 KSDSAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILH 386
            ......|.|:..:..||.....|.|.:: |..|.||:.||.:...:|..|.  |||||||||..:
plant   675 SGKGKLSEDMSGAQLLWKRSKPPGNATK-YNLTRFAITLNELTPGLKERLP--PTDSRLRPDQRY 736

  Fly   387 LEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGGYWDRKYD 451
            ||.|..:.|:.||.|||::||..||.::.    .|.||||......    :.:.|.||||:.:.|
plant   737 LENGEFEMANTEKLRLEQRQRQARKMQER----GWKPRWFMKEKGS----ESYRYKGGYWEARED 793

  Fly   452 NT 453
            .:
plant   794 GS 795

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3860	NP_001286802.1	Oxysterol_BP	26..441	CDD:279564	141/422 (33%)
ORP1C	NP_001319881.1	PH_ORP_plant	106..242	CDD:241448
ORP1C	NP_001319881.1	Oxysterol_BP	437..789	CDD:395990	145/428 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	260	1.000	Domainoid score	I482
eggNOG	1	0.900	-	-		E1_KOG1737
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000898
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810