DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3860 and ORP1A

DIOPT Version :10

Sequence 1:NP_001286802.1 Gene:CG3860 / 37825 FlyBaseID:FBgn0034951 Length:457 Species:Drosophila melanogaster
Sequence 2:NP_180659.2 Gene:ORP1A / 817653 AraportID:AT2G31020 Length:778 Species:Arabidopsis thaliana


Alignment Length:462 Identity:154/462 - (33%)
Similarity:232/462 - (50%) Gaps:97/462 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 HVE-RTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAA 72
            ||: |.:||..:...|.||:|:::|:.|||||:|:.:||..|||||.||:..|.:||:.||.:|:
plant   393 HVKRRKKLPDPVEKEKSVSLWSMIKDNIGKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLLDQAS 457

  Fly    73 Q---QEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGDY-----RIVCEQVSHHP 129
            :   :.:...|:..|||||||..||...|:.|||||:||||||   .||     |...|:|||||
plant   458 EWGKRGNNLMRILNVAAFAVSGYASTEGRICKPFNPMLGETYE---ADYPDKGLRFFSEKVSHHP 519

  Fly   130 PVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRL 194
            .:.|.|.:...:||.|..:.|.||||:|::::|.|.:|::|.. .|...|:.|...::|:|:|:|
plant   520 MIVACHCDGTGWKFWGDSNLKSKFWGRSIQLDPIGLLTLQFDD-GEIVQWSKVTTSIYNLILGKL 583

  Fly   195 WIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYFLYGKWTEFIKCCSAE 259
            :.:.||.|:|..:.. :...|.||......:|.|:|:|.|:|.:...:..|:|||.|.|      
plant   584 YCDHYGTMKIEGNGE-YSCKLKFKEQSMIDRNPHQVQGIVEDKNGKTVARLFGKWDESI------ 641

  Fly   260 SYVQFLKQGTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDVSSDSYPPMEQEGDIPKSD 324
            .|| .:.||                         |:|                            
plant   642 HYV-MVDQG-------------------------KVN---------------------------- 652

  Fly   325 SAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEE 389
                    :|..||....:|.|.:: |..|.|.:.||.:...:|..|.  |||||||||..:||:
plant   653 --------ESHLLWKRNKQPENPTK-YNLTRFGITLNELTPGLKEKLP--PTDSRLRPDQRYLEK 706

  Fly   390 GNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGGYWDRK----Y 450
            |..:..:.||.|||::||..|:.::.    .|.|:||:......|    :.|.||||:.:    :
plant   707 GEYEMGNAEKLRLEQRQRQAREMQER----GWKPKWFRKEKGSET----YRYIGGYWEARDSGSW 763

  Fly   451 DNTDTIF 457
            |:...||
plant   764 DDCPDIF 770

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3860NP_001286802.1 Oxysterol_BP 26..450 CDD:460126 144/435 (33%)
ORP1ANP_180659.2 PH_ORP_plant 91..229 CDD:241448
Oxysterol_BP 411..759 CDD:460126 144/431 (33%)
Blue background indicates that the domain is not in the aligned region.

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