DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3860 and Osbpl7

DIOPT Version :9

Sequence 1:	NP_001286802.1	Gene:	CG3860 / 37825	FlyBaseID:	FBgn0034951	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_011247566.1	Gene:	Osbpl7 / 71240	MGIID:	1918490	Length:	1004	Species:	Mus musculus

Alignment Length:	449	Identity:	169/449 - (37%)
Similarity:	234/449 - (52%)	Gaps:	87/449 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPAD 79
            |||......:||:|.||:|.|||||||::|||.|||||:.||||||.:||:.||.:|::...|.:
Mouse   629 LPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCE 693

  Fly    80 RMKYVAAFAVSALASNWERLG-KPFNPLLGETYELQKGD--YRIVCEQVSHHPPVSAFHAESKDF 141
            ||.|:|||||||.:|.:.|.| |||||:||||||.::.|  :|.:.||||||||:||.||||::|
Mouse   694 RMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENF 758

  Fly   142 KFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEI-- 204
            .|...:..|.||||||:|:.|.|||.|..|::.:.:.|..|..|:|||:.|:.|||.||::.|
Mouse   759 IFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRN 823

  Fly   205 TNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYFLYGKWTEFIKCCSAESYVQFLKQGT 269
            |..::.| ..:||..|...:.|:|.|:|.|...|...|:.|:|||.|.:
Mouse   824 TQDSSCH-CKITFCKAKYWSSNIHEVQGAVLSRSGRVLHRLFGKWHEGL---------------- 871

  Fly   270 RKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDVSSDSYPPMEQEGDIPKSDSAYSLDIPDS 334
                 |.|.|                                                    |..
Mouse   872 -----YRGPP----------------------------------------------------PGG 879

  Fly   335 TTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEK 399
            ..:|.....|.:....:.||.|||:||.:.|.:|  .||..||:|||||..:|||||:..|..:|
Mouse   880 QCIWKPNSMPPDHERNFGFTQFALELNELTSELK--RTLPSTDTRLRPDQRYLEEGNIQAAEAQK 942

  Fly   400 TRLEEKQRHTRKQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGGYW----DRKYDNTD 454
            .|:|:.||..|:..:..|... ..|:|:..|:...| :.|:.:..||    :..|.|.|
Mouse   943 RRIEQLQRDRRRVMEENNIVH-QARFFRRQTDSSGK-EWWVTNHTYWRLRAEPGYGNLD 999

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3860	NP_001286802.1	Oxysterol_BP	26..441	CDD:279564	160/419 (38%)
Osbpl7	XP_011247566.1	PH_ORP3_ORP6_ORP7	153..275	CDD:270104
Osbpl7	XP_011247566.1	Oxysterol_BP	640..987	CDD:366530	160/424 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1737
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740