DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3860 and Osbpl6

DIOPT Version :9

Sequence 1:	NP_001286802.1	Gene:	CG3860 / 37825	FlyBaseID:	FBgn0034951	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_017447182.1	Gene:	Osbpl6 / 311129	RGDID:	1308887	Length:	967	Species:	Rattus norvegicus

Alignment Length:	444	Identity:	168/444 - (37%)
Similarity:	231/444 - (52%)	Gaps:	81/444 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEH 76
            ||.|||.......:::|.||:|.|||||||::|||.|||||:.||.|||.|||::||.:|::.:.
  Rat   589 RTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDD 653

  Fly    77 PADRMKYVAAFAVSALASNWERLG-KPFNPLLGETYELQKGD--YRIVCEQVSHHPPVSAFHAES 138
            |.:||..|||||||...|.:.|.| |||||:||||||..:.|  :|...||||||||:||.|.||
  Rat   654 PYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCES 718

  Fly   139 KDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKME 203
            |:|.|...|..|.||||||:|:.|.||:.|..||:.:.|.|..|..|:|||:.||.|||.||::.
  Rat   719 KNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVT 783

  Fly   204 ITN-HATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYFLYGKWTEFIKCCSAESYVQFLKQ 267
            |.| .::..:..|||........|::.|:|.|.|.....::.|:|||.|.:.|..|
  Rat   784 IRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVA--------- 839

  Fly   268 GTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDVSSDSYPPMEQEGDIPKSDSAYSLDIP 332
                                                                            |
  Rat   840 ----------------------------------------------------------------P 840

  Fly   333 DSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASK 397
            .:..:|.....|:|...||.||.||::||.:|..:|.  .|.|||:|.|||...||||||:.|:.
  Rat   841 SAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKE--LLPPTDARFRPDQRFLEEGNLEAAAA 903

  Fly   398 EKTRLEEKQRHTRKQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGGYWDRKYD 451
            ||.|:||.||..|:..:..|.:. .|::||...:.:.: :.|:.:..||:.:.|
  Rat   904 EKQRVEELQRSRRRYMEENNLEH-IPKFFKKVIDANQR-EAWVSNDTYWELRKD 955

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3860	NP_001286802.1	Oxysterol_BP	26..441	CDD:279564	160/418 (38%)
Osbpl6	XP_017447182.1	PH_ORP3_ORP6_ORP7	66..188	CDD:270104
		PH	89..177	CDD:278594
		Oxysterol_BP	603..944	CDD:279564	159/417 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348349
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1737
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740