DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3860 and LOC100331149

DIOPT Version :9

Sequence 1:	NP_001286802.1	Gene:	CG3860 / 37825	FlyBaseID:	FBgn0034951	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_002667518.5	Gene:	LOC100331149 / 100331149	-ID:	-	Length:	487	Species:	Danio rerio

Alignment Length:	464	Identity:	233/464 - (50%)
Similarity:	286/464 - (61%)	Gaps:	42/464 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AEGDYAEH----VERTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYM 62
            ::||..:.    ..|:.|||.|.||..:|:|::||.|||.:||||||||:.||||||||||.|||
Zfish    58 SQGDQTQRNGVKNHRSALPAAMFSRNNISMWSVLKKCIGMELSKITMPVIFNEPLSFLQRLTEYM 122

  Fly    63 EYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGD--YRIVCEQV 125
            |:..|:..|...:....|||.||||||||:||.|||.||||||||||||||.:.|  :|.:.|||
Zfish   123 EHTYLIHRANASQDSIHRMKCVAAFAVSAVASQWERTGKPFNPLLGETYELVREDLGFRWISEQV 187

  Fly   126 SHHPPVSAFHAE--SKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHN 188
            |||||:||||||  .|||.|||:|.||:||||||||..|:|.:::|.|..:|:|:|||..|||||
Zfish   188 SHHPPISAFHAEGIKKDFMFHGSIYPKLKFWGKSVEAEPRGIISLELPGHSEAYTWTNPTCCVHN 252

  Fly   189 IIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYFLYGKWTEFI 253
            ||:|:|||||||.:||.||.||....|||||.|...|.||:|||::.|.|:..:..|||||||.:
Zfish   253 IIMGQLWIEQYGNVEIINHKTGERCCLTFKSCGIFGKELHKVEGYILDKSKKKVCALYGKWTECL 317

  Fly   254 KCCSAESYVQFLKQGTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDVSSDSYPPMEQEG 318
            ......::     :..||:|......:.||.                 |..:...|..||.|.|
Zfish   318 YSVDPAAF-----EAHRKSDVKRPEKSSTPS-----------------SHAEEEPDEMPPPEAE- 359

  Fly   319 DIPKSDSAYSLDIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPD 383
                   ...| ||.|..:|...|||.|..:||.||.||||||.:|..|:.  .|.|||.|||||
Zfish   360 -------TVQL-IPGSELIWRISPRPDNSGKYYAFTTFALQLNELDVEMEK--VLPPTDCRLRPD 414

  Fly   384 ILHLEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGGYWDR 448
            |..||.||:|.||.||.|||||||..||.|..:| ::|..|||...:||||...||||:..||.|
Zfish   415 IRALENGNIDIASAEKNRLEEKQRTARKDRSKSN-EEWKIRWFHQGSNPHTGAPDWLYNDNYWSR 478

  Fly   449 KYDNTDTIF 457
            .|.....|:
Zfish   479 NYSQLPDIY 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3860	NP_001286802.1	Oxysterol_BP	26..441	CDD:279564	217/418 (52%)
LOC100331149	XP_002667518.5	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589792
Domainoid	1	1.000	422	1.000	Domainoid score	I607
eggNOG	1	0.900	-	-		E1_KOG1737
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	440	1.000	Inparanoid score	I1634
OMA	1	1.010	-	-		QHG54233
OrthoDB	1	1.010	-	-		D166926at33208
OrthoFinder	1	1.000	-	-		FOG0000898
OrthoInspector	1	1.000	-	-		otm25134
orthoMCL	1	0.900	-	-		OOG6_103876
Panther	1	1.100	-	-	O	PTHR10972
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1685
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.810