Protein Alignment Pask and PSK2

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_014597.1
• Gene: PSK2 / 854111
• SGDID: S000005405
• Length: 1101
• Species: Saccharomyces cerevisiae
• Alignment Length: 920
• Identity: 210/920 - (22%)
• Similarity: 381/920 - (41%)
• Gaps: 190/920 - (20%)

  Fly    34 MGSHSQ---SRQNSSGMLNMMDASSFSMPPPNLHSSKVINPNKAIFTIDANTG--QIF------- 86
            :||.||   ..:....::::.|..      |....|::::|    ||...|:|  .||
Yeast   245 LGSKSQYNEYEEKHDDIVSLADIK------PQQDYSRILHP----FTSAKNSGPEAIFTCSQQYP 299

  Fly    87 ----IVNNKACQLLGYTSQELRNKGFFDLLNGKTESHISSLAEMQIEGDEGRVVLLSGK---VIE 144
                ..|:.||...|.:...::.....||::  |:|....|.::....|:.:.::.:|:   :::
Yeast   300 WNFKAANDLACLTFGISKNVIKALTLLDLIH--TDSRNFVLEKIMNAEDDNQEIVFTGETIPIVQ 362

  Fly   145 MKTKSGGK----ILVSLWIRQISSDGRHIAVAEPVERHICHISTD-RSGVITSVDSTT------- 197
            ..:.|...    |..|||.::  .:|..:.|.|........:..: |...:.|:..||
Yeast   363 PNSTSNNNVPNLIWASLWAKR--KNGLLVCVFEKTPCDYIDVMLNLRDFSVDSIIDTTHFLENFD 425

  Fly   198 --------------ATIFFYESVESVVGVS-----IVTLIPFIKLPDPDSREIPKSLRKQRATGR 243
                          .|:.|...:..:..||     ::..:.|.|:...|...:|.|:   |....
Yeast   426 KKKQQESTSPMTEKKTVKFANEIHDIGSVSHSLSKLIDDVRFGKVFSADDDLLPLSI---RVANH 487

  Fly   244 TTDNVKFPL-CLLIALDEDASAGYSHSGKTGLNITVWVFQN-----------LSGLIVVDD-IGN 295
            ..:...|.| ||              |......:|..|.:|           .:||.:||. ..:
Yeast   488 VNEERYFTLNCL--------------SENIPCAVTTSVLENEIKLKIHSLPYQAGLFIVDSHTLS 538

  Fly   296 ILMCNQPFSLLMFGYGQDKIMNMHISAILPNFGKDSREEKSPNVSNTSITSNDWEPDTDPLVV-- 358
            :|..|:..:..|||....::....::.::|     |..:....::.|....|...|:...||:
Yeast   539 LLSFNKSVAKNMFGLRLHELAGSSVTKLVP-----SLADMISYINKTYPMLNITLPENKGLVLTE 598

  Fly   359 ------------DNDS-----SLQSCKKSSTNRTAPNNEQSSVGDAHLSCNLENSSGLFCDLRQP 406
                        |.||     .|..|.|           ..::....:...:.|::.:...:...
Yeast   599 HFFRKIEAEMHHDKDSFYTSIGLDGCHK-----------DGNLIKVDVQLRVLNTNAVLLWITHS 652

  Fly   407 DDCTIDDILTPVNASNSFPADEFEV----GSQSQVNESSLDKAK------------------SAS 449
            .|..|::..|..:.......:|.:|    ||.|..::.|.:|..                  |.|
Yeast   653 RDVVIENYTTVPSQLPMLKENEIDVVGSRGSSSASSKKSSEKIPVNTLKAMADLSISSAETISNS 717

  Fly   450 TETCDASGSNPATR---------LLSSINGSFVGEAIHADGSVIEVVYSVLLQILPCSNRVYCIW 505
            .:..|.:..|...|         :.|:.|.::..:....|..  |:.:.:.|..:...::...:
Yeast   718 DDEVDLNQVNEKLRETSCGKVRGIESNDNNNYDDDMTMVDDP--ELKHKIELTKMYTQDKSKFV- 779

  Fly   506 VCRNPSTRLDGEKYNYANLTSTFNSMASTVEQSLGQVIKTTAAQNSSRPNSLSLVSKYEDELYLG 570
              ::.:.::| ||:           :...:|...|:.||....:...|.::|........|..:|
Yeast   780 --KDDNFKVD-EKF-----------IMRIIEPINGEEIKKETNELDKRNSTLKATYLTTPEANIG 830

  Fly   571 DYSKY-----YTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVPIEI 630
            ...:.     :|.::.:|.||||.||:...|.:..:|:.|.|.||::.....|:.|....:|.||
Yeast   831 SQKRIKKFSDFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEI 895

  Fly   631 HLLQTLN---HKNIVSVLDVFENDLFYQLVMEKHG--SGMDLWTFIERRPLMDEKLGSYIFRQVA 690
            .::.|||   .:||:.:||.||:|.:|.:....||  ..:||:..||.:..|.|.....:|:||.
Yeast   896 QIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVV 960

  Fly   691 DAVNYLHEQKILHRDIKDENIIIDQNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGNR 755
            .::.:||:|.|:||||||||:|:|.:..:||||||||.:::.|. |..|.||.:|.:||||.|:.
Yeast   961 ASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGP-FDVFVGTMDYAAPEVLGGSS 1024

  Fly   756 YVGPELEIWALGVTLYVLMFFENPFIDVEETLKAEIQIPKA--VSEQLSRLLSSMLNKDPKYRCT 818
            |.|...:||||||.||.:::.|||:.:::|.|:.|::..|:  |||:...|:..:|.::...|.|
Yeast  1025 YKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECISLIKRILTREVDKRPT 1089

  Fly   819 MHQLITDPWL 828
            :.::..|.||
Yeast  1090 IDEIYEDKWL 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914	24/120 (20%)
		PAS	182..350	CDD:441804	35/207 (17%)
		PAS	286..>325	CDD:238075	9/39 (23%)
		STKc_PASK	575..828	CDD:270906	99/264 (38%)
PSK2	NP_014597.1	STKc_PASK	840..1099	CDD:270906	99/259 (38%)