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Protein Alignment Pask and Nuak2

DIOPT Version :10

Sequence 1:	NP_611864.1	Gene:	Pask / 37824	FlyBaseID:	FBgn0034950	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_001181954.1	Gene:	Nuak2 / 74137	MGIID:	1921387	Length:	639	Species:	Mus musculus

Alignment Length:	482	Identity:	134/482 - (27%)
Similarity:	209/482 - (43%)	Gaps:	128/482 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   548 AQNSSRPNSLSLVSK----YEDELYLGDYSKY-----YTSIRQIGRGAYGYVNMAFRNSDRLLVI 603
            |..|:||.:..|:..    .:.:.....:.|:     |..:..:|:|.||.|..|..:|.||:.|
Mouse    20 ASESARPLADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAI 84

  Fly   604 TKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTLNHKNIVSV--------LDVFENDLFYQLVMEK 660
             |.|.|:|:..:     :|...:..||.::.:|||.:|:::        :.||||.....:|||
Mouse    85 -KSIRKDKIKDE-----QDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVME- 142

  Fly   661 HGSGMDLWTFIERRPLMDEKLGSYIFRQVADAVNYLHEQKILHRDIKDENIIIDQNFTIKLIDFG 725
            :.|..||:.:|..||.:.|:...:.|||:..|::|.|:..|:|||:|.|||::|.|..||:.|||
Mouse   143 YASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFG 207

  Fly   726 SATFMEEGKFFSTFYGTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLMFFENPFIDVEETLKAE 790
            .:....:|||..||.|:..|.|||::.|..|||||::.|:|||.||:|:....||         :
Mouse   208 LSNLYHKGKFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPF---------D 263

  Fly   791 IQIPKAVSEQLSR--------------LLSSMLNKDPKYRCTMHQLITDPWLTQEVNPSTFSFSW 841
            .|..|.:.:|:|.              |:..:|..:|..|.|:..:.:..|:           :|
Mouse   264 GQDHKTLVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWV-----------NW 317

  Fly   842 IVPCKAHEANPNLYFSGYLYSSTSVLSTISPQESFSHIEESSIGG--SDDARLAS-----HRTGH 899
                            ||       .:.:..||:...      ||  |.|...||     .|:..
Mouse   318 ----------------GY-------TTGVGEQEALRE------GGHPSGDFGRASMADWLRRSSR 353

  Fly   900 KLCVNEAKHNKMDTLYAKQFQLNTSVSNHELRVSLPDSSHTEIG----GSICSSKSENDIFKNKL 960
            .|..|.||    ...:.||              .:|....|..|    .|:..|:.|||:.:| |
Mouse   354 PLLENGAK----VCSFFKQ--------------HVPGGGSTVPGLERQHSLKKSRKENDMAQN-L 399

  Fly   961 Q--PCVSTYNVVSLHDVSTKPKKLDLK 985
            |  |.         .|.|::|.|..||
Mouse   400 QGDPA---------EDTSSRPGKSSLK 417

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.