DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pask and pim3

DIOPT Version :9

Sequence 1:	NP_611864.1	Gene:	Pask / 37824	FlyBaseID:	FBgn0034950	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_001030150.2	Gene:	pim3 / 565041	ZFINID:	ZDB-GENE-050809-111	Length:	320	Species:	Danio rerio

Alignment Length:	320	Identity:	93/320 - (29%)
Similarity:	152/320 - (47%)	Gaps:	28/320 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   524 LTSTFNSMA----STVEQSLGQVIKTTAAQNSSRPNSLSLVSKYEDELYLGDYSKYYTSIRQIGR 584
            |.|.|.|.:    :|....|...|:..||:....|                 :.|.|.....:|.
Zfish     2 LLSKFGSFSHICNTTNIDHLPVKIQLQAAKTEREP-----------------FEKVYHVGSVLGS 49

  Fly   585 GAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTL--NHKNIVSVLDV 647
            |.:|.|....|.||.|.|..|.:.||::.....:..   ..:|:||.||:.:  ..:.::.::|.
Zfish    50 GGFGTVYAGTRISDALPVAIKHVAKERVTEWGTING---SLIPLEIVLLKKVGSTFQGVIKLIDW 111

  Fly   648 FENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQVADAVNYLHEQKILHRDIKDENII 712
            :|....:.::||:.....||:.:|..:..:||......||||.:||.:.:...::||||||||::
Zfish   112 YERPDGWLIIMERPEMVKDLFDYITEKGALDEDTARGFFRQVLEAVRHCYSCGVVHRDIKDENLL 176

  Fly   713 ID-QNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLMFF 776
            :| :...:|||||||...::: ..::.|.||..|..||.:..:||.|....:|:|||.||.::..
Zfish   177 VDLRTGDLKLIDFGSGAILKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCG 240

  Fly   777 ENPFIDVEETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRCTMHQLITDPWLTQEVNPST 836
            :.||...||.|:..:...:.||....:|:...|...|..|.|:.|:....|:..|.||.|
Zfish   241 DIPFEHDEEILRGRLFFRRRVSPVCQQLIKWCLCLRPSDRPTLEQIFEHQWMRTEENPKT 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS_9	74..169	CDD:290162
		PAS	74..169	CDD:238075
		PAS_9	286..>335	CDD:290162
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	77/255 (30%)
		S_TKc	576..828	CDD:214567	77/254 (30%)
pim3	NP_001030150.2	STKc_PIM3	40..292	CDD:271004	77/255 (30%)
pim3	NP_001030150.2	Pkinase	41..292	CDD:278497	77/254 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2244
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940