Protein Alignment Pask and PIM1

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_001230115.1
• Gene: PIM1 / 5292
• HGNCID: 8986
• Length: 404
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 96/320 - (30%)
• Similarity: 152/320 - (47%)
• Gaps: 34/320 - (10%)

  Fly   524 LTSTFNSMASTVEQSLGQVIKTTAAQNSSRPNSLSLVSKYEDELYLGDYSKYYTSIRQIGRGAYG 588
            |.|..||:|.........:..|..|....:.   .|.|:|:    :|..         :|.|.:|
Human    93 LLSKINSLAHLRAAPCNDLHATKLAPGKEKE---PLESQYQ----VGPL---------LGSGGFG 141

  Fly   589 YVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKE------VPIEIHLLQTLN--HKNIVSVL 645
            .|....|.||.|.|..|.:.|:::        .|..|      ||:|:.||:.::  ...::.:|
Human   142 SVYSGIRVSDNLPVAIKHVEKDRI--------SDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLL 198

  Fly   646 DVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQVADAVNYLHEQKILHRDIKDEN 710
            |.||....:.|::|:.....||:.||..|..:.|:|....|.||.:||.:.|...:|||||||||
Human   199 DWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDEN 263

  Fly   711 IIIDQN-FTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLM 774
            |:||.| ..:|||||||...::: ..::.|.||..|..||.:..:||.|....:|:||:.||.::
Human   264 ILIDLNRGELKLIDFGSGALLKD-TVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMV 327

  Fly   775 FFENPFIDVEETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRCTMHQLITDPWLTQEVNP 834
            ..:.||...||.::.::...:.||.:...|:...|...|..|.|..::...||:...:.|
Human   328 CGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLP 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914
		PAS	182..350	CDD:441804
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	83/261 (32%)
PIM1	NP_001230115.1	STKc_PIM1	128..381	CDD:271002	85/274 (31%)