Protein Alignment Pask and mark3a

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: XP_021336197.1
• Gene: mark3a / 334300
• ZFINID: ZDB-GENE-030131-6232
• Length: 746
• Species: Danio rerio
• Alignment Length: 510
• Identity: 121/510 - (23%)
• Similarity: 210/510 - (41%)
• Gaps: 121/510 - (23%)

  Fly   576 YTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTLNHKN 640
            |..::.||:|.:..|.:|..      ::|...:..|:..:..:.....:::..|:.:::.|||.|
Zfish    57 YRLLKTIGKGNFAKVKLARH------ILTGSEVAIKMIDKTQLNPTSLQKLSREVTIMKNLNHPN 115

  Fly   641 IVSVLDVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQVADAVNYLHEQKILHRD 705
            ||.:.:|.|.:....|||| :.||.:::.::.....|.||.....|||:..||.|.|:::|:|||
Zfish   116 IVKLFEVIETEKTLFLVME-YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRD 179

  Fly   706 IKDENIIIDQNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGNRYVGPELEIWALGVTL 770
            :|.||:::|.:..||:.|||.:.....|....||.|:..|.:||:..|.:|.|||:::|:|||.|
Zfish   180 LKAENLLLDGDMNIKIADFGFSNEFMVGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL 244

  Fly   771 YVLMFFENPFIDV------EETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRCTMHQLITDPWLT 829
            |.|:....||...      |..|:.:.:||..:|.....||...|..:|..|.|:.|::.:.|:.
Zfish   245 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPAKRGTLEQIMKERWIN 309

  Fly   830 ----------------------------------QEVNPSTFSFSW--------IVPCKAHE--- 849
                                              ::::.|.|..::        ::..|.||
Zfish   310 SGFEDDELKPFTEPDADISDQKRIDVIVGMGFSKEKIHESLFKMNYDEVTAIYLLLGRKTHEEVS 374

  Fly   850 ---ANPNLYFSGYLYSSTSVLSTISPQE----SFSHIE-ESSIGGSDDARLASHRTGHKLCVNEA 906
               :|.||          ||..|....|    |.||:: :.||..|:..:...|.....:..|.|
Zfish   375 DSSSNSNL----------SVAKTRPSSEMNSQSPSHLKVQRSISSSESRKSRRHSEQVGVVANNA 429

  Fly   907 KHNKMDT--------------LYAKQFQLNTSVS------NHELRVSLPDS------SHTEIGGS 945
            ..|....              :.|::...::..|      |:..:..:||.      :...|.||
Zfish   430 LSNSKRVVPVTADSEVKQEGGVIARKLPNHSPPSPLLGNANNPNKTEIPDRKKGNSITSNNISGS 494

  Fly   946 ---------ICSSKSEND---IFKNKLQPCVSTYNV-----VSLHDVSTK--PKK 981
                     :|:.::..|   :..|..:..||....     .|.|.:||.  |.|
Zfish   495 GSMSRRNTYVCTERNNTDRLSVIPNGKENSVSLSPSSRDPGASTHSISTSVTPDK 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914
		PAS	182..350	CDD:441804
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	79/257 (31%)
mark3a	XP_021336197.1	STKc_MARK	56..308	CDD:270974	79/257 (31%)
		UBA_like_SF	326..368	CDD:473871	2/41 (5%)
		MARK1-3_C	647..744	CDD:213381