Protein Alignment Pask and Pim2

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_001165574.1
• Gene: Pim2 / 317366
• -ID: -
• Length: 311
• Species: Rattus norvegicus
• Alignment Length: 283
• Identity: 88/283 - (31%)
• Similarity: 142/283 - (50%)
• Gaps: 22/283 - (7%)

  Fly   563 YEDELYLGDYSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVP 627
            :|.|..||..         :|:|.:|.|....|.:||..|..|.|.:.::.....|.  |....|
  Rat    28 FEAEYRLGPL---------LGKGGFGTVFAGHRVTDRRQVAIKVISRNRVLGWSTVS--DSVTCP 81

  Fly   628 IEIHLLQTL----NHKNIVSVLDVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQ 688
            :|:.||..:    .|..::.:||.||....:.||:|:.....||:.:|..:..:.|......|.|
  Rat    82 LEVALLWKVGEGNGHPGVIRLLDWFETPEGFMLVLERPMPAQDLFDYITEKGPLGESCSRSFFTQ 146

  Fly   689 VADAVNYLHEQKILHRDIKDENIIIDQ-NFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLA 752
            |..||.:.|.:.::|||||||||:||. ..::|||||||...:.: :.::.|.||..|..||.::
  Rat   147 VVAAVQHCHARGVVHRDIKDENILIDLCRGSVKLIDFGSGALLHD-EPYTDFDGTRVYSPPEWIS 210

  Fly   753 GNRYVGPELEIWALGVTLYVLMFFENPFIDVEETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRC 817
            .::|......:|:|||.||.::..:.||...:|.|:||:..|..||.....|:...|...|..|.
  Rat   211 RHQYHALPATVWSLGVLLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPCSRP 275

  Fly   818 TMHQLITDPWL-----TQEVNPS 835
            ::.:::.|||:     .:.:|||
  Rat   276 SLEEILLDPWMQTPAEEKPINPS 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914
		PAS	182..350	CDD:441804
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	80/257 (31%)
Pim2	NP_001165574.1	Protein Kinases, catalytic domain	31..287	CDD:473864	84/267 (31%)