Protein Alignment Pask and nimk-1

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_496679.3
• Gene: nimk-1 / 186015
• WormBaseID: WBGene00009867
• Length: 503
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 135/560 - (24%)
• Similarity: 227/560 - (40%)
• Gaps: 112/560 - (20%)

  Fly   452 TCDASGSNPATRLLSSINGSFVGEAIHAD----GSVIEVVYSVLLQILPCSN---------RVYC 503
            |...|.|:..:|:..|  |......:.:|    .|::|  |:|..::....:         .|..
 Worm     5 TSSPSSSSMGSRMRDS--GGLARRTVRSDPPTYSSILE--YNVEEEVSEAESEESYEKPPEHVPA 65

  Fly   504 IWVCRNPSTRLDGEKYNYANLTSTFNSMASTVEQSLGQVIKTTAAQNSSRPNSLSL-----VSKY 563
            .:|   |:.|.|...|...:....||...|.|...:|:.:|..:.:.......|.|     |.|
 Worm    66 RFV---PTQRSDDGGYPAHHHHEAFNRTVSAVSLPVGKQLKDMSEKTQYERAILQLNNDPVVHK- 126

  Fly   564 EDELYLGDYSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSR-DCKEVP 627
              |:.||....:|...:::|.|.:..|.:....          :.|||:..:.|.|:: |.|...
 Worm   127 --EVALGRRIGFYRLGKELGAGNFSKVKLGVHQ----------LTKEKVAVKIMDKAKMDAKAQK 179

  Fly   628 I---EIHLLQTLNHKNIVSVLDVFENDLFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQV 689
            :   ||..::.:||.|||.:.:|.|......||:| :.||.:|:|::..|..:.|.....:|.|:
 Worm   180 LLSREIQAMEEMNHPNIVKLFEVVETLTRVHLVIE-YASGGELYTYVHERGKLTEGDAKPLFAQI 243

  Fly   690 ADAVNYLHEQKILHRDIKDENIIIDQNFTIKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGN 754
            ..||:::|.:.|:|||||.||::.....|:||:|||.:..::..:...||.|:..|.:||:....
 Worm   244 VSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFSCLVDREQMLRTFCGSPPYAAPELFQDT 308

  Fly   755 RYVGPELEIWALGVTLYVLMFFENPF-----IDVEETLKA-EIQIPKAVSEQLSRLLSSMLNKDP 813
            .|.|..:::|||||.|:.::....||     .|::..:.| :.|||..||...:.|:.|||..|.
 Worm   309 SYAGELVDVWALGVLLFFMLIGVTPFKAETVPDMKVLITAGKYQIPDYVSLLATELIKSMLKTDT 373

  Fly   814 KYRCTMHQLITDPWLTQEVNPSTFSFSWIVPCKAHEANPNLYFSGYLYSSTSVLSTISPQESFSH 878
            ..|..:              .|.....|:..|:..::          |.|....:.|..:|....
 Worm   374 GQRADI--------------DSVKKHFWMRDCRFTKS----------YLSIKATAKIDNEEEKKA 414

  Fly   879 I-------------------EESSIGGSDDARLASHRTGHKLCVNEAKHNKMDTLYAKQFQLNTS 924
            |                   ||:...|..||.:.::|                   ..|||:.:.
 Worm   415 IDDKVWKILNNYGIVKEMIVEENLDKGPRDAVVGTYR-------------------IVQFQVQSE 460

  Fly   925 VSNHELRVSLPD-SSHTEIGGSICSSKSENDIFKNKLQPC 963
            ::........|. ||.:...||..|.|..|...||:.:.|
 Worm   461 ITRLAKEKDEPQPSSSSFTNGSPTSVKDVNRKLKNRSKTC 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914
		PAS	182..350	CDD:441804
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	77/262 (29%)
nimk-1	NP_496679.3	STKc_NIM1	134..388	CDD:270977	78/278 (28%)