Protein Alignment Pask and Mark1

DIOPT Version :10

• Sequence 1: NP_611864.1
• Gene: Pask / 37824
• FlyBaseID: FBgn0034950
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: XP_038946210.1
• Gene: Mark1 / 117016
• RGDID: 619882
• Length: 794
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 119/463 - (25%)
• Similarity: 207/463 - (44%)
• Gaps: 78/463 - (16%)

  Fly   544 KTTAAQNSSRPNSLSLVSKYEDELYLGDYSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVITKFIL 608
            |:::.||..|..: |:.|..:::.::|:|....|    ||:|.:..|.:|..      |:|...:
  Rat    33 KSSSRQNIPRCRN-SITSATDEQPHIGNYRLQKT----IGKGNFAKVKLARH------VLTGREV 86

  Fly   609 KEKLCSQFMVKSRDCKEVPIEIHLLQTLNHKNIVSVLDVFENDLFYQLVMEKHGSGMDLWTFIER 673
            ..|:..:..:.....:::..|:.:::.|||.|||.:.:|.|.:....|||| :.||.:::.::..
  Rat    87 AVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVA 150

  Fly   674 RPLMDEKLGSYIFRQVADAVNYLHEQKILHRDIKDENIIIDQNFTIKLIDFGSATFMEEGKFFST 738
            ...|.||.....|||:..||.|.|::.|:|||:|.||:::|.:..||:.|||.:.....|....|
  Rat   151 HGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDT 215

  Fly   739 FYGTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLMFFENPFIDV------EETLKAEIQIPKAV 797
            |.|:..|.:||:..|.:|.|||:::|:|||.||.|:....||...      |..|:.:.::|..:
  Rat   216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYM 280

  Fly   798 SEQLSRLLSSMLNKDPKYRCTMHQLITDPWLT-----QEVNP-----------------STFSFS 840
            |.....||..:|..:|..|.::.|::.|.|:.     :|:.|                 .|..|:
  Rat   281 STDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYSEPELDLNDAKRIDIMVTMGFA 345

  Fly   841 ------WIVPCKAHEA---------NPNLYFSGYLYSSTSVLSTISPQ--------ESFSHIE-E 881
                  .:|..|..|.         .|..:..|...||.::.....|.        :|.:|:: :
  Rat   346 RDEINDALVSQKYDEVMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQ 410

  Fly   882 SSIGGSDDARLASHRTGHKL--CVNEAKHNKMDTLYAKQFQLNTSVSNHELRVSLPDSSHTEIGG 944
            .||..:...|..|...|..:  .|:          |.|:.|.|:..|  |.:......:...:|.
  Rat   411 RSISANQKQRRFSDHAGPSIPPAVS----------YTKRPQANSVES--EQKEEWDKDTARRLGS 463

  Fly   945 SICSSKSE 952
            :...||||
  Rat   464 TTVGSKSE 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pask	NP_611864.1	PAS	70..171	CDD:473914
		PAS	182..350	CDD:441804
		PAS	286..>325	CDD:238075
		STKc_PASK	575..828	CDD:270906	79/258 (31%)
Mark1	XP_038946210.1	STKc_MARK	59..311	CDD:270974	80/262 (31%)
		UBA_MARK1	331..371	CDD:270588	5/39 (13%)
		MARK1-3_C	695..792	CDD:213381