DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phm and Nhlrc3

DIOPT Version :9

Sequence 1:	NP_477225.1	Gene:	Phm / 37823	FlyBaseID:	FBgn0283509	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_766089.1	Gene:	Nhlrc3 / 212114	MGIID:	2444520	Length:	347	Species:	Mus musculus

Alignment Length:	86	Identity:	22/86 - (25%)
Similarity:	29/86 - (33%)	Gaps:	28/86 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 DLYLCTPIKVDPTTTYYIV----GFNPNATMNTAHHMLLYGCGEPGTSKTTWNCGEMNRASQEES 125
            :||      ||.|...|||    |.|......:...|:|:..||.||....:|.
Mouse   168 ELY------VDDTGEMYIVDGDGGLNNRLVKLSQDFMILWLRGENGTGPAKFNI----------- 215

  Fly   126 ASPCGPHSNS--QIVYAWARD 144
                 |||.:  .:...|..|
Mouse   216 -----PHSVTLDAVGRVWVAD 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phm	NP_477225.1	Cu2_monooxygen	51..179	CDD:279429	22/86 (26%)
Phm	NP_477225.1	Cu2_monoox_C	201..350	CDD:281675
Nhlrc3	NP_766089.1	NHL 1	47..93
		NHL	66..336	CDD:302697	22/86 (26%)
		YncE	<66..308	CDD:225926	22/86 (26%)
		NHL repeat	107..153	CDD:271320
		NHL 2	150..196		10/33 (30%)
		NHL repeat	166..205	CDD:271320	12/42 (29%)
		NHL 3	200..243		11/48 (23%)
		NHL repeat	213..250	CDD:271320	6/35 (17%)
		NHL repeat	258..299	CDD:271320
		NHL 4	294..338
		NHL repeat	308..335	CDD:271320
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2722
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030