Protein Alignment Phm and pghm-1

DIOPT Version :10

• Sequence 1: NP_477225.1
• Gene: Phm / 37823
• FlyBaseID: FBgn0283509
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_490898.1
• Gene: pghm-1 / 171746
• WormBaseID: WBGene00022144
• Length: 324
• Species: Caenorhabditis elegans
• Alignment Length: 305
• Identity: 139/305 - (45%)
• Similarity: 190/305 - (62%)
• Gaps: 12/305 - (3%)

  Fly    56 MPNVSPQTPDLYLCTPIKVDPTTTYYIVGFNPNATMNTAHHMLLYGCGEPGTSKTTWNCGEMNRA 120
            ||.|.|:. |.||||.:::..... |:.||....|..||||:||:||.|||:.:..|:|||||:.
 Worm    29 MPGVVPEA-DSYLCTSLELSDQEN-YLTGFKALTTKGTAHHILLFGCEEPGSDELVWDCGEMNKP 91

  Fly   121 SQEESASP-CGPHSNSQIVYAWARDAQKLNLPEGVGFKVGKNSPIKYLVLQVHYAHIDKFKDGST 184
            ..|...:| ||  |...|:||||.||..|.||:.|||:||.:|.|::||:||||.|..:    ..
 Worm    92 DDEMPRAPTCG--SKPAILYAWALDAPPLELPQDVGFRVGGDSNIRHLVMQVHYMHSKQ----EP 150

  Fly   185 DDSGVFLDYTEEPRKKLAGTLLLGTDGQIPAMKTEHLETACEVNEQKVLHPFAYRVHTHGLGKVV 249
            |::|:.:.:||||:.|||.|:||.|.|.:|..|||..||||.:.|..|:||||||.|||..||.|
 Worm   151 DETGLEITHTEEPQPKLAATMLLVTGGTLPRNKTESFETACMIEEDVVMHPFAYRTHTHRHGKEV 215

  Fly   250 SGYRVRTNSDGEQEWLQLGKRDPLTPQMFYNTSNTDPII-EGDKIAVRCTMQSTRHRTTKIGPTN 313
            ||:.|:.:...|..|..:|:|||...|||....:....| :||.:..||.:|:..:|...:|.|.
 Worm   216 SGWLVKEDQKHEDHWKLIGRRDPQLAQMFVPVEDQAMTIQQGDMVTARCILQNNENRDISMGATE 280

  Fly   314 EDEMCNFYLMYYVDHGETLNMKFCFSQGAPYYFWSNPDSGLHNIP 358
            ||||||||:||:.| ||.:....|:|.|||.|.|:. ::.|::||
 Worm   281 EDEMCNFYIMYWTD-GEVMQDNTCYSPGAPDYKWAR-EADLNHIP 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phm	NP_477225.1	Cu2_monooxygen	52..180	CDD:460053	59/124 (48%)
		Cu2_monoox_C	200..350	CDD:461021	71/150 (47%)
pghm-1	NP_490898.1	Cu2_monooxygen	27..145	CDD:460053	58/119 (49%)
		Cu2_monoox_C	166..316	CDD:461021	71/151 (47%)