Protein Alignment Sox14 and Sox30

DIOPT Version :10

• Sequence 1: NP_476894.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001414119.1
• Gene: Sox30 / 689918
• RGDID: 1586382
• Length: 770
• Species: Rattus norvegicus
• Alignment Length: 805
• Identity: 155/805 - (19%)
• Similarity: 240/805 - (29%)
• Gaps: 315/805 - (39%)

  Fly     4 KPNQATTEPP-----------------------LSLRPGTV-----------PTVPATTPARPAT 34
            ||.|....||                       |.|||..:           |..|...|.:|.|
  Rat    84 KPEQVLLLPPGPLLPQAPDEGAAAAASSAQARLLQLRPELLLLPPQSAADGGPCRPELRPMQPRT 148

  Fly    35 ITIQ------------------------RRHPAPKADSTPHTLPPFSPSPSPASSPSPAPAQT-- 73
            :.::                        |...|.|.|.|...|.........|...:...::.
  Rat   149 LLVKAEKQELGAGLDLSVGSRRTTEAGPRASRAAKLDGTGKALDGRRGDEKKAKLEAEEASRDAL 213

  Fly    74 ------------PGAQKTQ---------------SQAAITHPAAVASPSAPVAAAAPKTPKTPEP 111
                        .|..||:               :...:.|.:..|..:.|.:|..|.......|
  Rat   214 KGGEGRSLLAIGEGVIKTEEPERLRDDCRLGTEATSNGLVHSSKEAILAQPPSAFGPHQQDLRFP 278

  Fly   112 RSTHT-HTHTHSQHFSPPPRE-------------SEMDGERSPSHSGHEMTLSMDGIDSSLVFGS 162
            .:.|| ......|...|||.|             .:|.....||     :.:....:..:::...
  Rat   279 LTLHTVPPGARIQFQGPPPSELIRLSKVPLTPVPIKMQSLLEPS-----VKIETKDVPLTVLPSD 338

  Fly   163 ARVPVNSSTPYSDATRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQL 227
            |.:|   .||:|      |...||:||||||||||:::.|..:.:..|..:|||||.:||..|..
  Rat   339 AGIP---DTPFS------KDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNK 394

  Fly   228 LSKDDKQPYIIEAEKLRKLHMIEYPNYKYRPQK-KQTRSPGSLKPNQDADGCEARNDTTNNNNSL 291
            ||::.|:||..||:|:::.|..|:|.:.|:|:. |:.|.|.|:.        ...:.||.|
  Rat   395 LSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSVS--------NVFSGTTQN---- 447

  Fly   292 TTLAINGTTTAGRKSKRSTSTCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPSAD 356
             .::.|.||....:|                          |.|.|             ::|...
  Rat   448 -IISTNPTTIYPYRS--------------------------PTYSV-------------VIPGLQ 472

  Fly   357 NLISYQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSL 421
            |.|::...|..|...|.                       :..|.|..|:             :|
  Rat   473 NTITHPVGEAPPAIQLP-----------------------TPAVQRPSPI-------------TL 501

  Fly   422 TQSQHNQSDPTAGLMDNISDISPINDREELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGKPLN 486
            .|...:.:.|.|        :.|               |.|...|            ||..:..:
  Rat   502 FQPSVSSTGPVA--------VPP---------------PSLTPRP------------SLPPQRFS 531

  Fly   487 EPVFDSEDNIVNDANLHSASHQIPPYVPDSHDCFAEDCGGDSSSHQVEFEVVRPQTVTMTMTCTL 551
            .|   |:.::          |::|              .|.|.|      |.||..|::..|..:
  Rat   532 GP---SQTDV----------HRLP--------------SGTSRS------VKRPTPVSLESTNRI 563

  Fly   552 PYGGPDAGHTTFQADDFNAIPSAAEDSECSILTT-------------------------SNSPQI 591
            |.|...| |..|...........|..|.|...|.                         ...|:.
  Rat   564 PAGASTA-HARFATSPIQPPKEYAGVSTCPRSTPIPPATPIPHSHVYQPPPLGHPATLFGTPPRF 627

  Fly   592 GFNGSSFVEADAI--GSTCTYAQQ-----DYTGSVIET--HNDLNYAAHDNNGALLA-----YTF 642
            .|:...|:.....  .|||.|::.     ::..|:.|.  :.:..|..|:   |:.:     |.|
  Rat   628 SFHHPYFLPGPHYFPSSTCPYSRPPFGYGNFPSSMPECLGYYEDRYQKHE---AIFSALNRDYPF 689

  Fly   643 EDLPPQPTGSHLEFNTNKYEFASYY 667
            .|.|.:.|.|....:....:...||
  Rat   690 RDYPDEHTHSEDSRSCESMDGPPYY 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_476894.1	HMG-box_SoxC	186..261	CDD:438838	34/75 (45%)
Sox30	NP_001414119.1	None