| Sequence 1: | NP_001286801.1 | Gene: | Sox14 / 37822 | FlyBaseID: | FBgn0005612 | Length: | 669 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_008872.1 | Gene: | SOX10 / 6663 | HGNCID: | 11190 | Length: | 466 | Species: | Homo sapiens |
| Alignment Length: | 558 | Identity: | 121/558 - (21%) |
|---|---|---|---|
| Similarity: | 194/558 - (34%) | Gaps: | 201/558 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 43 APKADSTPHTLPPFSPSPSPASSP-----------SPAPAQTPGAQKTQSQAAITHPAAVASPSA 96
Fly 97 PVAAAAPKTPKTPEPRSTHTHTHTHSQHFSPPPRESEMDGERSPSHSGHEMTLSMDGIDSSLVFG 161
Fly 162 SARVPVNSSTPYSDATRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQ 226
Fly 227 LLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRPQKKQT---------------------------- 263
Fly 264 ------RSPGSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAGRKSKRSTSTCQSGSASKRL 322
Fly 323 RNDSGDTSSKP------------KYEVKMESAEQLNSADI--ILP---SADNLISYQSSEY---- 366
Fly 367 -------------------LPLSTLSNADCDEKLHSELS--SGPLESRENLSEVVNRFLPLFLGG 410
Fly 411 NEDSQLGVSSLTQSQHNQSDPTAGLMD-NISDISPINDREELTEEVMRYLPYLEVNPSSDGLTLK 474
Fly 475 VESSSLLGKPLNEPVFDS-EDNIVNDANLHSASHQIPP 511 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sox14 | NP_001286801.1 | SOX-TCF_HMG-box | 186..257 | CDD:238684 | 41/70 (59%) |
| SOX10 | NP_008872.1 | Sox_N | 12..93 | CDD:315171 | 19/131 (15%) |
| Dimerization (DIM). /evidence=ECO:0000303|PubMed:31194875 | 62..102 | 10/47 (21%) | |||
| SOX-TCF_HMG-box | 103..173 | CDD:238684 | 40/69 (58%) | ||
| Nuclear export signal | 134..145 | 5/10 (50%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 160..199 | 8/38 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 212..274 | 17/76 (22%) | |||
| Transactivation domain (TAM). /evidence=ECO:0000303|PubMed:31194875 | 228..310 | 18/91 (20%) | |||
| Transactivation domain (TAC). /evidence=ECO:0000303|PubMed:31194875 | 353..466 | 25/138 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 354..375 | 4/35 (11%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 433..466 | 6/26 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..67 | 14/105 (13%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165148483 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0527 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000028 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.740 | |||||