Protein Alignment Sox14 and SOX5

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_016875377.1
• Gene: SOX5 / 6660
• HGNCID: 11201
• Length: 793
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 114/434 - (26%)
• Similarity: 162/434 - (37%)
• Gaps: 113/434 - (26%)

  Fly    13 PLSLRPGTVPTVPATTPA---------RPATITIQRRHPAPKADSTP-------------HTLPP 55
            |:.|.|.|:....|.||.         ..|.:...:..|..|....|             || ..
Human   345 PVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTSIHT-DK 408

  Fly    56 FSPSPSPASSPSPA-PAQTPGAQKTQSQAAITHPAA-------VASPSAPVAAAAPKTPKTPEPR 112
            .:.||.|.|....| |.......||....:.|.|.:       :.|.:.|:.|:.|....:|..|
Human   409 STNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSAR 473

  Fly   113 -STHTHTHTHS----------QHFSPPPRESE-MDG----------------------------- 136
             ||..:.:.|.          |......||.: :||
Human   474 VSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQL 538

  Fly   137 ------ERSPSHSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDATRTKKHSPGHIKRPMNAFM 195
                  |...||:..:..||.|.      .|||  .|:.|..|.::.....:.| ||||||||||
Human   539 AVKQNEEGKFSHAMMDFNLSGDS------DGSA--GVSESRIYRESRGRGSNEP-HIKRPMNAFM 594

  Fly   196 VWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRPQK 260
            ||::.|||||.:..||:||:.|||.||.||:.::..:||||..|..:|.|.|:.:||:|||:|:.
Human   595 VWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRP 659

  Fly   261 KQT-------RSPGSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAGRKSKRSTSTCQSGSA 318
            |:|       ...|..|........|.|........:...:|..|....|       :...:|..
Human   660 KRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPG-------AIAMAGMP 717

  Fly   319 SKRLRNDSGDTSSKPK---------YEVKMES---AEQLNSADI 350
            |..|.::....||.|:         |.||.|.   .|::.:.||
Human   718 SPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDI 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	40/70 (57%)
SOX5	XP_016875377.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148495
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740