Protein Alignment Sox14 and PXN

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_016875215.1
• Gene: PXN / 5829
• HGNCID: 9718
• Length: 1135
• Species: Homo sapiens
• Alignment Length: 590
• Identity: 117/590 - (19%)
• Similarity: 187/590 - (31%)
• Gaps: 190/590 - (32%)

  Fly     6 NQATTEPPLSLRPGTVPT---VPATT-----PARPATITIQRRHPA-------PKADSTPHTLPP 55
            ::|.:.|||   ||.:..   ||.|.     .|.|.|....:|:..       |..:|....|..
Human   171 DEANSSPPL---PGALSPLYGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELES 232

  Fly    56 FSPSPSPASSPSPAPAQTP-GAQKTQSQAAITHPAAV-------------ASPSAPVAAAAP--- 103
            ..|||.||.:.:.....:| ....||.|..|:..:|.             .:.|:.||.:||
Human   233 SVPSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKTSSSTVALSAPGLS 297

  Fly   104 --------KTPKTPEPRST---------------HTH----THTHSQHFSPPPRESEMD------ 135
                    ..|.:|.|..:               ||.    |....:...||...|.:|
Human   298 SSAPSSYCSLPPSPPPMPSVFLPPTTIPSPRGQGHTPEFPCTEQSGRGLLPPVAPSWLDLAGLGV 362

  Fly   136 -----GERSPSHSGHEMTLSMD--GID-------SSLVFGSAR---VPVNSSTPYSDATRTKKHS 183
                 ..||||..|....:..:  |.|       :|.:.|:.|   ||...||...:
Human   363 MPDTFNSRSPSVEGSLWAVGTESQGRDWRHLPTITSELSGAPRCHTVPCAGSTALQE-------- 419

  Fly   184 PGHIKRPMNA--------FMVWSQMERRKIC--ERTPDLHNAEISKELGRRWQLLSKD-----DK 233
            ||..:.|..:        ...|.|....::.  ||.|....|       |.:|.:::.     |:
Human   420 PGEPQGPPASPSCPEEALAATWEQPWASEVFGPERMPPSGAA-------RSFQEVTEPAVVAVDR 477

  Fly   234 QPYIIEAEKLRKLHMIEYPNYKYRPQKKQTRSPGSL----------------KPNQDADGCEARN 282
            |....:...|.:.|.::....:..|.:..:.||.|:                :|.|..:...:..
Human   478 QAIFPDTWTLTEEHGLQQERPRPEPGRLGSSSPASVTTEQLGAKMTERGSVARPTQGPETPRSPE 542

  Fly   283 DTT-------NNNNSLTTLAINGT-------TTAGRKSKRSTSTCQSGSA-------SKRLRNDS 326
            .||       .....|......||       :|:|:.......:.:||.|       |.|.|.|.
Human   543 GTTEAATQDGKEQPELPCAMAMGTPSTTERISTSGQIRSVIRRSWESGHAHPMSREPSPRRRLDP 607

  Fly   327 GDTSSKPKYE-----------VKMESAEQLNSADIILPSADN------LISYQSSEYLPLSTLSN 374
            ...|..|..|           ::.|:.|...:|.   |||.:      :|:.|     |....:.
Human   608 ATLSRTPSQEQLIAELQGRLGIQPEAEEPAEAAG---PSAQDWLTEGVIITVQ-----PRGKRAG 664

  Fly   375 ADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQHNQSDPTAGLMDNI 439
            ....||:.....| |:..|..:|.:.:..:||           :...|.:..:.|.|...|:.:
Human   665 GQLVEKVVFPPGS-PIPLRRTISVLASPSVPL-----------LQHRTDAAASSSSPLPSLLAS- 716

  Fly   440 SDISP 444
            |.:.|
Human   717 SPLGP 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	13/85 (15%)
PXN	XP_016875215.1	Paxillin	60..259	CDD:281527	23/90 (26%)
		LIM1_Paxillin_like	902..954	CDD:259830
		LIM2_Paxillin	961..1012	CDD:188791
		LIM3_Paxillin_like	1020..1072	CDD:188724
		LIM4_Paxillin	1079..1130	CDD:188795

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900