Protein Alignment Sox14 and pxnb

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_021334029.1
• Gene: pxnb / 565130
• ZFINID: ZDB-GENE-130530-697
• Length: 1197
• Species: Danio rerio
• Alignment Length: 632
• Identity: 132/632 - (20%)
• Similarity: 196/632 - (31%)
• Gaps: 191/632 - (30%)

  Fly    29 PARPATITIQRRHPAPK---ADSTPHTLP----PFSPSPS------------------------- 61
            |....|.|....||.|.   :.|...|||    .|||.||
Zfish   311 PLFEQTTTTAEIHPPPTTTVSKSLSPTLPAESRQFSPGPSSFELHIVEDSGEPGAVPLPSNGVFK 375

  Fly    62 --------PASSPSPAPAQTPGAQKTQSQAAITHPAAVASPSAPVAAAAPKT-PKTPEPRSTHTH 117
                    |||||..:||...|.     .:||...|::.|..........:| |.|..||
Zfish   376 SYSRLSPPPASSPRFSPAPDLGL-----DSAIDVSASLLSSEVESLVVLSQTIPMTSAPR----- 430

  Fly   118 THTHSQHFSPPPRESEMDGERSPS----HSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDATR 178
                .|:.||.       .|.|||    :||                      :||.:|     .
Zfish   431 ----GQYLSPV-------REGSPSAKLMNSG----------------------LNSYSP-----N 457

  Fly   179 TKKHSP-------------GHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSK 230
            ||..||             ..:..|.:..:..|:.|.:.: ...|.|..:.:.......:..|.|
Zfish   458 TKSPSPRSSPAISRVNERVSPLMTPASIDLYLSRPETKPL-SPVPSLPRSPLPAVSESSFLSLPK 521

  Fly   231 DDKQPYIIEAEKLRKLHMIEYPNYKYRPQKKQTRSP-GSLKPNQDADGCEARNDTTNNNNSLTTL 294
            ....|.||....  .|.:.:.|:.|   |:.....| .||||:.:....|...|     ::|..|
Zfish   522 ALSPPPIIPTSP--TLGVSKSPSPK---QESAYLEPVVSLKPHLEPPTYEPSLD-----DALDKL 576

  Fly   295 AINGTTTAGRKSKRSTSTCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPS----- 354
                  .|...|:....|..:.|||.:|       :|:.:.|:..||....:.:||...:
Zfish   577 ------LAMSFSRPENETHITASASSQL-------TSEAQPEIYEESIVAADRSDIHPDTHTESE 628

  Fly   355 -ADNLISYQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGV 418
             .|.|:..||.   ..|.|..||.:.|:..|...|.:......|.:.:...|....|..|:|:.:
Zfish   629 MGDGLLEDQSD---CRSDLDWADMELKMAYEGPDGSMTPMTEASWMDDSLTPSSCPGTPDAQMDL 690

  Fly   419 SSLTQSQHNQSDPTAGLMDNISDISPINDREELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGK 483
            ..|..         ||.||.||....|......|:|:....|...     |||..:.....:..|
Zfish   691 PMLHM---------AGTMDRISASGHIKSVIRRTKEIQNVHPMYR-----DGLIRRKMGPLIFHK 741

  Fly   484 PLNEPVFDSEDNIVND-------ANLHSASHQIPPYVPDSHDCFAEDC--------GGDSSSHQV 533
            .      :|:|.::.:       |....|..|.|      .|...|..        ..:..:..|
Zfish   742 S------NSQDRLIEELQGKLGIARKEKAKKQQP------DDWLTEGVIVMSNPKRSREDHNRDV 794

  Fly   534 EFEVVRPQTVTMTMTCTLPYGGPDAGHTTFQADDFNAIPSAAEDSEC 580
            :..::.|::........||...|.....          |..||:.:|
Zfish   795 DKIIIPPESPLPQRKMILPPQSPPMPRP----------PPPAEEPKC 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	13/70 (19%)
pxnb	XP_021334029.1	Paxillin	96..272	CDD:308898
		Atrophin-1	<178..684	CDD:331285	98/447 (22%)
		LIM1_Paxillin_like	964..1016	CDD:259830
		LIM2_Paxillin_like	1023..1074	CDD:188723
		LIM3_Paxillin_like	1082..1134	CDD:188724
		LIM4_Paxillin	1141..1192	CDD:188795

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900