DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sox14 and pdlim1

DIOPT Version :9

Sequence 1:	NP_001286801.1	Gene:	Sox14 / 37822	FlyBaseID:	FBgn0005612	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001017870.1	Gene:	pdlim1 / 550568	ZFINID:	ZDB-GENE-030131-5227	Length:	322	Species:	Danio rerio

Alignment Length:	191	Identity:	42/191 - (21%)
Similarity:	73/191 - (38%)	Gaps:	38/191 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   408 LGGNEDSQ-LGVSSLTQ-SQHNQSDPTAGLMDNISDISPINDREELTEEVMRYLPYLEVNPSSDG 470
            :||.:..| |.:|.:|. |:..|:|...|  |.|..|.     .|.|:.:.......::....|.
Zfish    18 VGGKDFEQPLTISRVTPGSKAAQADLCMG--DMILAID-----GESTDGMTHLEAQNKIKACGDE 75

  Fly   471 LTLKVE-SSSLLGKPLNEPVFDSEDNIVN--DANLHSASHQIPPYVPDSHDCFAEDCGGDSSSHQ 532
            :.|.:: |.|.:..||     .:||...|  ..||...:.|...::..:|:..|
Zfish    76 MALSIDRSESKMWSPL-----VTEDGKTNPYKMNLAKTNTQEEKHIGSAHNRSA----------- 124

  Fly   533 VEFEVVRPQTVTMTMTCTLPYGGPDAGHTTFQADDFNA----IPSAAEDSECSILTTSNSP 589
            :.|....|:.||.      .|..|...:::....:||:    :.:.|..||.|..:..:.|
Zfish   125 MPFNSASPRVVTN------QYNNPAGLYSSENIKNFNSAVDEVQTTATSSEASRNSDPSKP 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684
pdlim1	NP_001017870.1	PDZ_signaling	2..80	CDD:238492	17/68 (25%)
		DUF4749	133..223	CDD:292558	11/53 (21%)
		LIM_CLP36	253..304	CDD:188832
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900