DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox14 and Pdlim1

DIOPT Version :9

Sequence 1:	NP_001286801.1	Gene:	Sox14 / 37822	FlyBaseID:	FBgn0005612	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_059061.1	Gene:	Pdlim1 / 54133	RGDID:	68324	Length:	327	Species:	Rattus norvegicus

Alignment Length:	180	Identity:	35/180 - (19%)
Similarity:	54/180 - (30%)	Gaps:	61/180 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 TITIQR---------------RHP-----APKADSTPH-------TLPPFSPSPSPASSPSPAPA 71
            |:|:.|               |||     |.:.....|       :..||:.||:|.:.......
  Rat    78 TLTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPGTRVITNQY 142

  Fly    72 QTPGAQKTQSQAAITHPAAVASPSAPVAAAAPKTPKTPEP--------RSTHTHTHTHSQHFSPP 128
            .:|....:....:..:.|..:..||....|..:....|.|        .|.........|..:.|
  Rat   143 NSPTGLYSSENISNFNNAVESKTSASGEEANSRPSAQPHPSGGLIIDKESEVYKMLQEKQELNEP 207

  Fly   129 PRES----------EMDGERSPSH-SGHEMTLSMDGIDSSLVFGSARVPV 167
            |::|          |.||:..|:. ||               |.|.:.||
  Rat   208 PKQSTSFLVLQEILESDGKGDPNKPSG---------------FRSVKAPV 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684
Pdlim1	NP_059061.1	PDZ_signaling	5..81	CDD:238492	1/2 (50%)
		DUF4749	136..228	CDD:292558	15/91 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..186		5/24 (21%)
		LIM_CLP36	258..309	CDD:188832
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900