DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox14 and Pdlim1

DIOPT Version :9

Sequence 1:	NP_001286801.1	Gene:	Sox14 / 37822	FlyBaseID:	FBgn0005612	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_058557.2	Gene:	Pdlim1 / 54132	MGIID:	1860611	Length:	327	Species:	Mus musculus

Alignment Length:	200	Identity:	45/200 - (22%)
Similarity:	73/200 - (36%)	Gaps:	50/200 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 DSGDTSSKPKYEVKMESAEQLNSADIILPSADNLISYQSSEYLPLSTLSNADCDEKLHSELSSGP 389
            |..||||....|.:.:          |...|||:            ||:.:..::|:.|     |
Mouse    54 DGEDTSSMTHLEAQNK----------IKGCADNM------------TLTVSRSEQKIWS-----P 91

  Fly   390 LESRE--------NLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQH---NQSDPTAGL--MDNISD 441
            |.:.|        ||:......|.:....|..:....:|...|..   ||.:...||  .:|||:
Mouse    92 LVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPSTRVITNQYNSPTGLYSSENISN 156

  Fly   442 I-SPINDREELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGK------PLNEPVFDSEDNIVND 499
            . :.:..:...:.|.....|.::.:||.   :|.::..|.:.|      .||||...|...:|..
Mouse   157 FNNAVESKTSASGEEANSRPVVQPHPSG---SLIIDKDSEVYKMLQEKQELNEPPKQSTSFLVLQ 218

  Fly   500 ANLHS 504
            ..|.|
Mouse   219 EILES 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684
Pdlim1	NP_058557.2	PDZ_signaling	5..81	CDD:238492	12/48 (25%)
		DUF4749	136..228	CDD:292558	21/90 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..184		3/22 (14%)
		LIM_CLP36	258..309	CDD:188832
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900