Protein Alignment Sox14 and Sox15

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 742
• Identity: 166/742 - (22%)
• Similarity: 259/742 - (34%)
• Gaps: 250/742 - (33%)

  Fly    51 HTLPPFSPSPSPASSPSPAPAQTPGA---------------QKTQSQAAITHPAAVASPSAPVAA 100
            |.|..::....|..|.:|..:.:.|:               .::.|.|.|.|....:..|:|
  Fly    12 HLLTNYNSKKYPHVSRTPEYSHSTGSDYPEHGGYLTDGRLMHESNSDAGIYHVRQGSEHSSP--- 73

  Fly   101 AAPKTPKTPEPRST-----H-------THTHTHSQHFSPPPRESEM---DGERSPSHSGHEMTLS 150
                :..:|..:|:     |       .|:|:|    ||.|..|..   .|..|.|.....:.|.
  Fly    74 ----SLHSPAIQSSGYENEHLNEAVLAAHSHSH----SPMPMVSSAYVGGGTASGSLINSNIPLL 130

  Fly   151 MDGIDS-----------SLVFG--------SARVPVNSSTPYS---------------------- 174
            ..|.:|           .:|.|        ::..|:.:::.:|
  Fly   131 GGGGNSVLNKFLSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAPNCGYLERHKPLP 195

  Fly   175 -------DATRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDD 232
                   ..|::|......|:|||||||||:::||:|:.:..||||||::||.||::|:.|:..|
  Fly   196 ADLKYRPGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQD 260

  Fly   233 KQPYIIEAEKLRKLHMIEYPNYKYRPQKKQTRSPGSLKPNQDADGCEARNDTTNNNNSLTTLAIN 297
            ::||:.|||:||.:||.|:|||||||::::.....:::|........:.|..|..:.|...||..
  Fly   261 RRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATP 325

  Fly   298 GTTTAGRKSKRST--STCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPSADNLIS 360
            ...||.......|  |||.|      ...:.|.::....||..::.....:|.|
  Fly   326 PLATASSSYTTPTDESTCNS------TNQNHGQSTPGGLYEQPLKPTYSPSSVD----------- 373

  Fly   361 YQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQ 425
                      ..||||..|::.|..::.|               |..|
  Fly   374 ----------CYSNADSTEQIESLAANCP---------------PALL----------------- 396

  Fly   426 HNQSDPTAGLMDN------ISDISPINDREELTEEVMR------------------YLPYLEVNP 466
             |:|.||.|..||      ::..||....:...|::.:                  |.....:.|
  Fly   397 -NESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAATYPLAP 460

  Fly   467 SS------DGLTLKVESSSLL--GKPLN----EPVFDSE-DNIVNDANLHSASHQIPPYVPDSHD 518
            :|      .|:.:...:..||  |..:.    .||..|| ||..:..|..||..|         .
  Fly   461 TSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNSISALQQ---------H 516

  Fly   519 CFAEDCGGDSSSHQVEFEVVRPQTVTMTMTC--------------TLP----YGGPDAGHTTFQA 565
            |........||...:....:...||:|...|              .||    ||........:|:
  Fly   517 CNVVTSTPSSSGGTMPTSEMSSYTVSMADNCGNLRLSMNELSGNEYLPSANAYGMQYEDFLRYQS 581

  Fly   566 DDFNAIPSAAEDSECSILTTSNSPQIGFNGSSFVEADAIGSTCTY---AQQDYTGSVIETHNDLN 627
            :|.:...||.|..|    |||:|              |.|..|..   ..|:|.          :
  Fly   582 NDMDYSTSAVEHKE----TTSDS--------------ASGQKCLKYPDTNQNYD----------D 618

  Fly   628 YAAHDNNGALLAYT----FEDLPPQPT 650
            |.|...:.|:|..|    :..||..||
  Fly   619 YEAEAYSNAMLPATAASYYTQLPYPPT 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	40/70 (57%)
Sox15	NP_523739.2	SOX-TCF_HMG-box	214..285	CDD:238684	40/70 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451316
Domainoid	1	1.000	49	1.000	Domainoid score	I4418
eggNOG	1	0.900	-	-		E1_KOG0527
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.870