Protein Alignment Sox14 and Sox4

DIOPT Version :10

• Sequence 1: NP_476894.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001258134.1
• Gene: Sox4 / 364712
• RGDID: 1309488
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 144/558 - (25%)
• Similarity: 201/558 - (36%)
• Gaps: 189/558 - (33%)

  Fly   131 ESEMDGERSPSHSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDATRTKKHSPGHIKRPMNAFM 195
            |:.:.||.|.|.:|.|:     ||.||...||..    |:...:|.....|...|||||||||||
  Rat    12 EALLAGESSDSGAGLEL-----GIASSPTPGSTA----STGGKADDPSWCKTPSGHIKRPMNAFM 67

  Fly   196 VWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRPQK 260
            ||||:|||||.|::||:|||||||.||:||:||...||.|:|.|||:||..||.:||:|||||:|
  Rat    68 VWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIQEAERLRLKHMADYPDYKYRPRK 132

  Fly   261 KQTRSPGSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAGRKSKRSTSTCQSGSASKRLRND 325
            |                                 ..:|.|.||     |.:|.:.|....::...
  Rat   133 K---------------------------------VKSGNTGAG-----SAATAKPGEKGDKVAGG 159

  Fly   326 SGDT-----------SSKPKYEVKMESAEQLNSADIILPSA-------DNLISYQSSEYLPLSTL 372
            ||..           ||||  ..|.....::..:.:..|.|       ....:..|.|...|..|
  Rat   160 SGHAGSGHAGGGAGGSSKP--APKKSCGPKVAGSSVGKPHAKFVPAGGGKAAASFSPEQAALLPL 222

  Fly   373 SNADCDEKLHSELSSGPLESRENLSEVV--------NRFLPLFLGGNEDSQLGVSSLTQSQHNQS 429
            .......|:.:..::.|..|....|.:.        .:...::|.|:    ||.|         :
  Rat   223 GEPAAVYKVRTPSAATPAASSSPSSALATPAKHPADKKVKRVYLFGS----LGAS---------A 274

  Fly   430 DPTAGLMDNISDISPINDREELTEEVMRYLPYLEVNP--SSDGLTLKVESSSLLGKPLNEPVFDS 492
            .|..||..:.....|:.             .|.:..|  |.||.:|...||:......:....|.
  Rat   275 SPVGGLGASADPSDPLG-------------LYEDGGPGCSPDGRSLSGRSSAASSPAASRSPADH 326

  Fly   493 EDNIVNDANLHSAS---HQIPPYVPDSHDCFAEDCGGDSSSHQVEFEVVRPQTVTMTMTCTLPYG 554
            .    ..|:|.:||   ...|.:...|....:....|.|||.. |||
  Rat   327 R----GYASLRAASPAPSSAPSHASSSLSSSSSSSSGSSSSDD-EFE------------------ 368

  Fly   555 GPDAGHTTFQADDFNAIPSAAEDSECSILTTSNSPQIGFNGSSFVEADAIGSTCTYAQQDYTGSV 619
                       ||.                      :..|.||..|:.::||..       :.|.
  Rat   369 -----------DDL----------------------LDLNPSSNFESMSLGSFS-------SSSA 393

  Fly   620 IETHNDLNYAAHDNNGALLAYTFEDLPPQP-TGSHLEF 656
            ::...|.|:                   :| :|||.||
  Rat   394 LDRDLDFNF-------------------EPGSGSHFEF 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_476894.1	HMG-box_SoxC	186..261	CDD:438838	53/74 (72%)
Sox4	NP_001258134.1	HMG-box_SoxC	58..133	CDD:438838	53/74 (72%)