Protein Alignment Sox14 and Sox18

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001019952.1
• Gene: Sox18 / 311723
• RGDID: 1311718
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 444
• Identity: 113/444 - (25%)
• Similarity: 169/444 - (38%)
• Gaps: 137/444 - (30%)

  Fly    90 AVASP-SAPVAAAAPKTPKTPE--PRSTHTHTHTHSQHFSPPPRESEMDGERSPSHSGHEMTLSM 151
            |.|.| ..||...:|.:|.:|.  |||              |||..|         ||.
  Rat    28 AAAEPRGLPVTNVSPTSPASPSSLPRS--------------PPRSPE---------SGR------ 63

  Fly   152 DGIDSSLVFGSARVPVNSSTPYSDATRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAE 216
                    :|..|    .....:|..|        |:|||||||||::.||:::.::.||||||.
  Rat    64 --------YGFGR----GERQTADELR--------IRRPMNAFMVWAKDERKRLAQQNPDLHNAV 108

  Fly   217 ISKELGRRWQLLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRP-QKKQTRS----------PGSLK 270
            :||.||:.|:.|:..:|:|::.|||:||..|:.::||||||| :|||.|.          ||.::
  Rat   109 LSKMLGKAWKELNTAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKVRRLEPGLLLPGLVQ 173

  Fly   271 PNQDADGCEARNDTTNNNNSLTTLAIN----GTTTAGRKSKRSTSTCQSGSAS------------ 319
            |:...:...|.:.:..:...|.||...    |..|..|.   .....:||.||
  Rat   174 PSAPPEPFAAASGSARSFRELPTLGAEFDGLGLPTPERS---PLDGLESGEASFFPPPLAPEDCA 235

  Fly   320 -KRLRND-SGDTSSKPKYEVKMESAEQLNSADIILPSADNLISYQSSEYLPLSTLSNADCDEKLH 382
             :..|.. :.:.:..|.:......||.|.:|....|.|.          |...||.
  Rat   236 LRAFRAPYAPELARDPSFCYGSSLAEALRTAPPAAPLAG----------LYYGTLG--------- 281

  Fly   383 SELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQHNQSDPTAGLMDNISDISPIND 447
               :.||..:            ||.......|..|...|        :|||.|..::
  Rat   282 ---TPGPFPN------------PLSPPPEAPSLEGTEQL--------EPTADLWADV-------- 315

  Fly   448 REELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGKPLNEPVFDSEDNIVNDAN 501
              :|| |..:||......|.:..|...|..:.|..:.::.|...|..:.::||:
  Rat   316 --DLT-EFDQYLNCSRTRPDATALPYHVALAKLGPRAMSCPEESSLISALSDAS 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	36/70 (51%)
Sox18	NP_001019952.1	SOX-TCF_HMG-box	78..149	CDD:238684	37/78 (47%)
		Sox17_18_mid	191..239	CDD:403331	10/50 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342358
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840