DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sox14 and Pdlim2

DIOPT Version :9

Sequence 1:NP_001286801.1 Gene:Sox14 / 37822 FlyBaseID:FBgn0005612 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_001007623.1 Gene:Pdlim2 / 290354 RGDID:1359203 Length:349 Species:Rattus norvegicus


Alignment Length:285 Identity:61/285 - (21%)
Similarity:93/285 - (32%) Gaps:78/285 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   294 LAINGTTTAGRKSKRSTSTCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQLN---SADII---- 351
            :||||.:........:.|..:..::..||:.|...|:          |..|:|   |.|::    
  Rat    50 VAINGESAESMLHAEAQSKIRQSASPLRLQLDRSQTA----------SPGQINGEGSLDMLATRF 104

  Fly   352 ---LPSADNLISYQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNED 413
               |.:..|..|.|.|     :..|.|....:..|..|:.|..|            |:.|.|...
  Rat   105 QGSLRTHHNSQSSQRS-----ACFSPASLSPRPDSPFSTPPPTS------------PIALSGENV 152

  Fly   414 SQLGVSSLTQS-----QHNQSDPTAGLMDNISDISPINDREELTEEVMRYLPYLEVNPSSDGL-T 472
            ......|||.|     .|:.:.|...........||       ::..:|.|.:....|||..| :
  Rat   153 IGCSFQSLTHSPGLAATHHLTYPGQPTSQQAGHSSP-------SDSTVRVLLHSPGRPSSPRLSS 210

  Fly   473 LKVESSSLLGKPLNE-------PVFDSEDNIVNDANLHSASHQIPPYVPDS-------------- 516
            |.:|..|.:.|.|.|       |...|...::.:|.........|.:||.|              
  Rat   211 LDLEEDSEVFKMLQENRQGRAAPRQSSSFRLLQEALEAEERGGTPAFVPSSLSPKASLPTSRALA 275

  Fly   517 -----HDCFAEDCGGDSSSHQVEFE 536
                 |.|  |.|..:.|:..|..:
  Rat   276 TPPKLHTC--EKCSVNISNQAVRIQ 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sox14NP_001286801.1 SOX-TCF_HMG-box 186..257 CDD:238684
Pdlim2NP_001007623.1 PDZ_signaling 9..80 CDD:238492 7/29 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..95 7/32 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 108..147 12/55 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 168..212 10/50 (20%)
DUF4749 <190..252 CDD:292558 15/61 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 250..272 4/21 (19%)
LIM_Mystique 283..335 CDD:188833 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1703
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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