DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sox14 and PDLIM3

DIOPT Version :9

Sequence 1:NP_001286801.1 Gene:Sox14 / 37822 FlyBaseID:FBgn0005612 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_055291.2 Gene:PDLIM3 / 27295 HGNCID:20767 Length:364 Species:Homo sapiens


Alignment Length:205 Identity:48/205 - (23%)
Similarity:68/205 - (33%) Gaps:59/205 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 SLRPGTVPTVPATTPAR------PATITIQRRHPAPKADSTPHTLPPFSPSPSPASSPS-PAPAQ 72
            ::||     .|...|.|      |:.|........|.:.||..|:.|.....:...:|: |...:
Human   120 NIRP-----KPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEME 179

  Fly    73 TPGAQKTQSQAAITHPAAVASP-------SAPVAAAAPKTPKTPEPRSTHTHTHTHSQHFSPPPR 130
            .||.:...:|  ...|..:.|.       ...|:.|..:||...||.:            |.|| 
Human   180 LPGVKIVHAQ--FNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTA------------SVPP- 229

  Fly   131 ESEM-----DGERSPS---HSGHEMTLS---MDGIDSSLV-FGSARVPVNSSTPYSDATRTKKH- 182
            ||::     |....|:   .||....|.   .||.|.... ..|.|.||           ||.| 
Human   230 ESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPV-----------TKVHG 283

  Fly   183 -SPGHIKRPM 191
             |.|..:.|:
Human   284 GSGGAQRMPL 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sox14NP_001286801.1 SOX-TCF_HMG-box 186..257 CDD:238684 1/6 (17%)
PDLIM3NP_055291.2 PDZ_signaling 2..80 CDD:238492
DUF4749 184..263 CDD:374237 19/93 (20%)
LIM_ALP 294..346 CDD:188834 48/205 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1703
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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