DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox14 and Pdlim2

DIOPT Version :9

Sequence 1:	NP_001286801.1	Gene:	Sox14 / 37822	FlyBaseID:	FBgn0005612	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001240665.1	Gene:	Pdlim2 / 213019	MGIID:	2384850	Length:	349	Species:	Mus musculus

Alignment Length:	124	Identity:	32/124 - (25%)
Similarity:	42/124 - (33%)	Gaps:	22/124 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RRHPAPKADSTPHTLPPFSPSPSPASSPSPAPAQTPGAQKTQSQAAITHPAAVASPSAPVAAAAP 103
            |.|...::........|.|.||.|.|..|..|..:|.|...:.....:..:...||.  :|||
Mouse   109 RTHRDSQSSQRSACFSPVSLSPRPCSPFSTPPPTSPVALSKEDMIGCSFQSLTHSPG--LAAA-- 169

  Fly   104 KTPKTPEPRSTHTHTHTHSQHFSPPPRESEMDGERSPSHSGHEMTLSMDGIDSSLVFGS 162
                         |..|:..|     ..|:..|..|||.|...:.|...|..||..|.|
Mouse   170 -------------HHLTYPGH-----PTSQQAGHSSPSDSAVRVLLHSPGRPSSPRFSS 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684
Pdlim2	NP_001240665.1	PDZ_signaling	9..80	CDD:238492
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	74..147		11/37 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	169..212		16/62 (26%)
		DUF4749	<198..252	CDD:406377	5/13 (38%)
		LIM_Mystique	283..335	CDD:188833
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900