Protein Alignment Sox14 and Sox7

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_035576.1
• Gene: Sox7 / 20680
• MGIID: 98369
• Length: 380
• Species: Mus musculus
• Alignment Length: 369
• Identity: 100/369 - (27%)
• Similarity: 143/369 - (38%)
• Gaps: 104/369 - (28%)

  Fly   181 KHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLRK 245
            |.|...|:|||||||||::.||:::..:.|||||||:||.||:.|:.|:...|:||:.|||:||.
Mouse    39 KSSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRL 103

  Fly   246 LHMIEYPNYKYRP-QKKQTR------SPGSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAG 303
            .||.:|||||||| :|||.:      .||.|..:...|     .:|....|.:           |
Mouse   104 QHMQDYPNYKYRPRRKKQGKRLCKRVDPGFLLSSLSRD-----QNTLPEKNGI-----------G 152

  Fly   304 RKSKRSTSTCQSGSASKRLRN----------DSGDTSSKPKYEVKMESAEQLNSADIILPSADNL 358
            |..|........|:....|.:          .|.||     |...:.:..:::..|.:.|.
Mouse   153 RGEKEDRGEYSPGATLPGLHSCYREGAAAAPGSVDT-----YPYGLPTPPEMSPLDALEPE---- 208

  Fly   359 ISYQSSEYLPLSTLSNADCDEK----LHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVS 419
                       .|..::.|.|:    .|.....||..|.|        |.|..|  :....||..
Mouse   209 -----------QTFFSSSCQEEHGHPHHLPHLPGPPYSPE--------FTPSPL--HCSHPLGSL 252

  Fly   420 SLTQSQHNQSDPTAGLMDNISDISPINDREELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGKP 484
            :|.||      |...:|.::|...|          ...|..:...:|....|...:   ..|..|
Mouse   253 ALGQS------PGVSMMSSVSGCPP----------SPAYYSHATYHPLHPNLQAHL---GQLSPP 298

  Fly   485 LNEPVFDSEDNIVN------------DANLHSASHQIPPYVPDS 516
            ...|.||:.|.:..            |..|::..|      |||
Mouse   299 PEHPGFDTLDQLSQVELLGDMDRNEFDQYLNTPGH------PDS 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	40/70 (57%)
Sox7	NP_035576.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..43		2/3 (67%)
		SOX-TCF_HMG-box	44..115	CDD:238684	40/70 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..167		7/43 (16%)
		Sox_C_TAD	175..378	CDD:288887	41/217 (19%)
		Required for beta-catenin-binding	323..328		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838584
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870