Protein Alignment Sox14 and Sox4

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_033264.2
• Gene: Sox4 / 20677
• MGIID: 98366
• Length: 440
• Species: Mus musculus
• Alignment Length: 546
• Identity: 141/546 - (25%)
• Similarity: 202/546 - (36%)
• Gaps: 165/546 - (30%)

  Fly   131 ESEMDGERSPSHSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDATRTKKHSPGHIKRPMNAFM 195
            |:.:.||.|.|.:|.|:     ||.||...||..    |:...:|.....|...|||||||||||
Mouse    12 EALLAGESSDSGAGLEL-----GIASSPTPGSTA----STGGKADDPSWCKTPSGHIKRPMNAFM 67

  Fly   196 VWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRPQK 260
            ||||:|||||.|::||:|||||||.||:||:||...||.|:|.|||:||..||.:||:|||||:|
Mouse    68 VWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIQEAERLRLKHMADYPDYKYRPRK 132

  Fly   261 K------QTRSPGSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAGRKSKRSTSTCQSGSAS 319
            |      ...|..:.||.:..|.....:...            |::.||..:..|:......|..
Mouse   133 KVKSGNAGAGSAATAKPGEKGDKVAGSSGHA------------GSSHAGGGAGGSSKPAPKKSCG 185

  Fly   320 KRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPSADNLISYQSSEYLPLSTLSNADCDEKLHSE 384
            .::   :|.:..||             .|.::........:..|.|...|..|.......|:.:.
Mouse   186 PKV---AGSSVGKP-------------HAKLVPAGGSKAAASFSPEQAALLPLGEPTAVYKVRTP 234

  Fly   385 LSSGPLESRENLSEVV--------NRFLPLFLGGNEDSQLGVSSLTQSQHNQSDPTAGLMDNISD 441
            .::.|..|....|.:.        .:...::|.|:    ||.|         :.|..||..:...
Mouse   235 SAATPAASSSPSSALATPAKHPADKKVKRVYLFGS----LGAS---------ASPVGGLGASADP 286

  Fly   442 ISPINDREELTEEVMRYLPYLEVNP--SSDGLTLKVESSSLLGKPLNEPVFDSEDNIVNDANLHS 504
            ..|:.             .|.:..|  |.||.:|...||:......:....|..    ..|:|.:
Mouse   287 SDPLG-------------LYEDGGPGCSPDGRSLSGRSSAASSPAASRSPADHR----GYASLRA 334

  Fly   505 AS---HQIPPYVPDSHDCFAEDCGGDSSSHQVEFEVVRPQTVTMTMTCTLPYGGPDAGHTTFQAD 566
            ||   ...|.:...|....:....|.|||.. |||                             |
Mouse   335 ASPAPSSAPSHASSSLSSSSSSSSGSSSSDD-EFE-----------------------------D 369

  Fly   567 DFNAIPSAAEDSECSILTTSNSPQIGFNGSSFVEADAIGSTCTYAQQDYTGSVIETHNDLNYAAH 631
            |.                      :..|.||..|:.::||..       :.|.::...|.|:
Mouse   370 DL----------------------LDLNPSSNFESMSLGSFS-------SSSALDRDLDFNF--- 402

  Fly   632 DNNGALLAYTFEDLPPQP-TGSHLEF 656
                            :| :|||.||
Mouse   403 ----------------EPGSGSHFEF 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	50/70 (71%)
Sox4	NP_033264.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		16/54 (30%)
		SOX-TCF_HMG-box	58..129	CDD:238684	50/70 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..211		18/110 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..258		3/23 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	272..382		32/187 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838604
Domainoid	1	1.000	109	1.000	Domainoid score	I6352
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		otm42653
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.840