Protein Alignment Sox14 and Sox2

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_035573.3
• Gene: Sox2 / 20674
• MGIID: 98364
• Length: 319
• Species: Mus musculus
• Alignment Length: 299
• Identity: 92/299 - (30%)
• Similarity: 139/299 - (46%)
• Gaps: 63/299 - (21%)

  Fly   180 KKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLR 244
            :|:||..:|||||||||||:.:|||:.:..|.:||:||||.||..|:|||:.:|:|:|.||::||
Mouse    36 QKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR 100

  Fly   245 KLHMIEYPNYKYRPQK---------KQTRSPGSLKP-------------------NQDADGCEAR 281
            .|||.|:|:|||||::         |.|...|.|.|                   ||..|.....
Mouse   101 ALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHM 165

  Fly   282 NDTTNNNNSLTT----------LAINGTTTAGRKSKRSTSTCQ--SGSASKRLRNDSGDTSSKPK 334
            |..:|.:.|:..          |..:|........:...|..|  |.::|:...|.|      |.
Mouse   166 NGWSNGSYSMMQEQLGYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGS------PT 224

  Fly   335 YEVKMESAEQLNSADIILPSADNLISYQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEV 399
            |.:   |..|..:..:.|.|..:::..::|...|:.|.|:       ||.   .|.::.: |.::
Mouse   225 YSM---SYSQQGTPGMALGSMGSVVKSEASSSPPVVTSSS-------HSR---APCQAGD-LRDM 275

  Fly   400 VNRFLPLFLGGNEDSQLGVSSLTQSQHNQSDPTAGLMDN 438
            ::.:||   |.........|.|..:||.||.|..|...|
Mouse   276 ISMYLP---GAEVPEPAAPSRLHMAQHYQSGPVPGTAIN 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	41/70 (59%)
Sox2	NP_035573.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		3/6 (50%)
		SOX-TCF_HMG-box	42..113	CDD:238684	41/70 (59%)
		SOXp	112..202	CDD:403523	16/89 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	247..267		6/29 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..319		6/13 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840